STOKE THERAPEUTICS INC

NASDAQ: STOK (Stoke Therapeutics, Inc.)

Last update: 25 Nov, 3:44PM

29.82

-0.52 (-1.71%)

Previous Close 30.34
Open 30.94
Volume 1,946,200
Avg. Volume (3M) 1,184,543
Market Cap 1,703,233,408
Price / Earnings (TTM) 43.85
Price / Earnings (Forward) 204.08
Price / Sales 8.63
Price / Book 5.53
52 Weeks Range
5.35 (-82%) — 38.69 (29%)
Earnings Date 4 Nov 2025
Profit Margin 26.33%
Operating Margin (TTM) 70.15%
Diluted EPS (TTM) 0.820
Quarterly Revenue Growth (YOY) 3,661.10%
Total Debt/Equity (MRQ) 1.20%
Current Ratio (MRQ) 8.41
Operating Cash Flow (TTM) 69.54 M
Levered Free Cash Flow (TTM) 60.20 M
Return on Assets (TTM) 7.81%
Return on Equity (TTM) 20.50%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Bullish Mixed
Biotechnology (Global) Bullish Mixed
Stock Stoke Therapeutics, Inc. Bullish Bullish

AIStockmoo Score

-1.0
Analyst Consensus 1.5
Insider Activity -1.5
Price Volatility -4.5
Technical Moving Averages -2.5
Technical Oscillators 2.0
Average -1.00

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Stoke Therapeutics Inc is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. Its proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) approach, Stoke is developing antisense oligonucleotides (ASOs) to restore naturally-occurring protein levels selectively. Its first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome. The company provides early programs focused on multiple targets, including haploinsufficiency diseases of the central nervous system and eye, to up-regulate the protein expression of the underlying disease gene in a mutation-agnostic manner.

Sector Healthcare
Industry Biotechnology
Investment Style Small Core
% Held by Insiders 4.57%
% Held by Institutions 114.81%

Ownership

Name Date Shares Held
Skorpios Trust 30 Sep 2025 2,256,181
52 Weeks Range
5.35 (-82%) — 38.69 (29%)
Price Target Range
25.00 (-16%) — 39.00 (30%)
High 39.00 (BTIG, 30.79%) Buy
Median 32.00 (7.31%)
Low 25.00 (JP Morgan, -16.16%) Hold
Average 31.80 (6.64%)
Total 4 Buy, 1 Hold
Avg. Price @ Call 24.95
Firm Date Target Price Call Price @ Call
BTIG 05 Nov 2025 39.00 (30.78%) Buy 22.82
13 Oct 2025 39.00 (30.78%) Buy 30.34
Canaccord Genuity 05 Nov 2025 28.00 (-6.10%) Buy 22.82
Wedbush 05 Nov 2025 32.00 (7.31%) Buy 22.82
JP Morgan 03 Nov 2025 25.00 (-16.16%) Hold 26.10
Needham 10 Oct 2025 35.00 (17.37%) Buy 30.19
Name Avg. Buy ($) Avg. Sell ($) Net Quantity Net Value ($)
KRAINER ADRIAN R. - 30.34 -40,472 -1,227,920
Aggregate Net Quantity -40,472
Aggregate Net Value ($) -1,227,920
Aggregate Avg. Buy ($) -
Aggregate Avg. Sell ($) 30.34
Name Holder Date Type Quantity Price Value ($)
KRAINER ADRIAN R. Director 24 Nov 2025 Automatic sell (-) 40,472 30.34 1,227,920
Date Type Details
01 Dec 2025 Announcement Stoke Therapeutics and Biogen Announce Presentations at the 2025 American Epilepsy Society Annual Meeting
18 Nov 2025 Announcement Stoke Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)
17 Nov 2025 Announcement Stoke Therapeutics and Biogen Announce Publication of Two-Year Natural History Data Demonstrating the Severity of Dravet Syndrome, Including Frequent Seizures and Significant Cognitive and Behavioral Impairments
17 Nov 2025 Announcement Biogen and Stoke Therapeutics Announce Publication of Two-Year Natural History Data Demonstrating the Severity of Dravet Syndrome, Including Frequent Seizures and Significant Cognitive and Behavioral Impairments
05 Nov 2025 Announcement Stoke Therapeutics to Present at the Guggenheim 2nd Annual Healthcare Innovation Conference
04 Nov 2025 Announcement Stoke Therapeutics Reports Third Quarter 2025 Financial Results and Provides Business Updates
30 Oct 2025 Announcement Stoke Therapeutics to Host Webcast and Conference Call to Discuss Third Quarter 2025 Business and Financial Updates
20 Oct 2025 Announcement Stoke Therapeutics Presents Two-Year Natural History Data from Patients with Autosomal Dominant Optic Atrophy (ADOA)
16 Oct 2025 Announcement Stoke Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)
09 Oct 2025 Announcement Biogen and Stoke Therapeutics Present New Data at the 54th Child Neurology Society (CNS) Annual Meeting that Support the Potential of Zorevunersen as a Disease-Modifying Medicine for Dravet Syndrome
09 Oct 2025 Announcement Stoke Therapeutics and Biogen Present New Data at the 54th Child Neurology Society (CNS) Annual Meeting that Support the Potential of Zorevunersen as a Disease-Modifying Medicine for Dravet Syndrome
06 Oct 2025 Announcement Stoke Therapeutics Appoints Ian F. Smith as Chief Executive Officer
16 Sep 2025 Announcement Stoke Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)
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