ALNYLAM PHARMACEUTICALS INC

NASDAQ: ALNY (Alnylam Pharmaceuticals, Inc.)

Last update: 5 days ago, 12:44PM

359.81

-1.54 (-0.43%)

Previous Close 361.35
Open 361.55
Volume 398,263
Avg. Volume (3M) 1,396,780
Market Cap 47,536,201,728
Price / Earnings (TTM) 1,240.73
Price / Earnings (Forward) 49.02
Price / Sales 14.82
Price / Book 202.20
52 Weeks Range
205.87 (-42%) — 495.55 (37%)
Earnings Date 30 Oct 2025
Profit Margin -11.49%
Operating Margin (TTM) 3.04%
Diluted EPS (TTM) -2.11
Quarterly Revenue Growth (YOY) 20.20%
Total Debt/Equity (MRQ) 2,358.25%
Current Ratio (MRQ) 3.04
Operating Cash Flow (TTM) -45.11 M
Levered Free Cash Flow (TTM) 223.09 M
Return on Assets (TTM) -1.79%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Bullish Mixed
Biotechnology (Global) Bullish Mixed
Stock Alnylam Pharmaceuticals, Inc. Bearish Bullish

AIStockmoo Score

0.3
Analyst Consensus -0.5
Insider Activity NA
Price Volatility 2.0
Technical Moving Averages 0.0
Technical Oscillators -0.5
Average 0.25

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Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia. It also has several clinical programs across various therapeutic areas: genetic medicines; cardio-metabolic diseases; hepatic infectious diseases, and CNS/ocular diseases. Upfront fees from research partnerships have boosted Alnylam's cash levels, and the company stands to see additional milestones and royalties from drugs commercialized under collaboration partnerships.

Sector Healthcare
Industry Biotechnology
Investment Style Mid Core
% Held by Insiders 3.81%
% Held by Institutions 97.56%
52 Weeks Range
205.87 (-42%) — 495.55 (37%)
Price Target Range
351.00 (-2%) — 530.00 (47%)
High 530.00 (Truist Securities, 47.30%) Buy
Median 486.50 (35.21%)
Low 351.00 (Leerink Partners, -2.45%) Hold
Average 466.60 (29.68%)
Total 7 Buy, 3 Hold
Avg. Price @ Call 364.93
Firm Date Target Price Call Price @ Call
B of A Securities 30 Jan 2026 462.00 (28.40%) Buy 338.06
12 Jan 2026 529.00 (47.02%) Buy 370.91
HC Wainwright & Co. 30 Jan 2026 510.00 (41.74%) Buy 338.06
Morgan Stanley 30 Jan 2026 408.00 (13.39%) Hold 338.06
Barclays 28 Jan 2026 527.00 (46.47%) Buy 349.58
RBC Capital 20 Jan 2026 465.00 (29.23%) Buy 355.53
Wells Fargo 20 Jan 2026 376.00 (4.50%) Hold 355.53
11 Nov 2025 479.00 (33.12%) Hold 451.95
Needham 12 Jan 2026 529.00 (47.02%) Buy 370.91
Truist Securities 08 Jan 2026 530.00 (47.30%) Buy 399.40
Leerink Partners 15 Dec 2025 351.00 (-2.45%) Hold 391.50
Stifel 11 Dec 2025 508.00 (41.18%) Buy 412.63
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