ALNYLAM PHARMACEUTICALS INC

NASDAQ: ALNY (Alnylam Pharmaceuticals, Inc.)

Last update: 26 Aug, 3:08PM

451.20

7.56 (1.70%)

Previous Close 443.64
Open 444.31
Volume 1,054,302
Avg. Volume (3M) 1,072,788
Market Cap 59,142,844,416
Price / Earnings (Forward) 50.51
Price / Sales 23.76
Price / Book 236.29
52 Weeks Range
205.87 (-54%) — 469.81 (4%)
Earnings Date 30 Oct 2025
Profit Margin -11.49%
Operating Margin (TTM) 3.04%
Diluted EPS (TTM) -2.11
Quarterly Revenue Growth (YOY) 20.20%
Total Debt/Equity (MRQ) 2,358.25%
Current Ratio (MRQ) 3.04
Operating Cash Flow (TTM) -45.11 M
Levered Free Cash Flow (TTM) 223.09 M
Return on Assets (TTM) -1.79%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Mixed Bearish
Biotechnology (Global) Mixed Bearish
Stock Alnylam Pharmaceuticals, Inc. Bullish Bullish

AIStockmoo Score

0.0
Analyst Consensus 1.5
Insider Activity -1.5
Price Volatility -3.0
Technical Moving Averages 1.0
Technical Oscillators 2.0
Average 0.00

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Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia. It also has several clinical programs across various therapeutic areas: genetic medicines; cardio-metabolic diseases; hepatic infectious diseases, and CNS/ocular diseases. Upfront fees from research partnerships have boosted Alnylam's cash levels, and the company stands to see additional milestones and royalties from drugs commercialized under collaboration partnerships.

Sector Healthcare
Industry Biotechnology
Investment Style Mid Core
% Held by Insiders 3.81%
% Held by Institutions 97.56%

Ownership

Name Date Shares Held
Regeneron Pharmaceuticals, Inc. 30 Jun 2025 4,444,445
52 Weeks Range
205.87 (-54%) — 469.81 (4%)
Price Target Range
384.00 (-14%) — 583.00 (29%)
High 583.00 (Citigroup, 29.21%) Buy
Median 465.00 (3.06%)
Low 384.00 (Jefferies, -14.89%) Buy
Average 469.20 (3.99%)
Total 18 Buy, 2 Hold
Avg. Price @ Call 411.57
Firm Date Target Price Call Price @ Call
B of A Securities 17 Sep 2025 520.00 (15.25%) Buy 451.73
11 Jul 2025 359.00 (-20.43%) Buy 314.94
Goldman Sachs 16 Sep 2025 566.00 (25.44%) Buy 461.24
Evercore ISI Group 11 Sep 2025 515.05 (14.15%) Buy 468.58
BMO Capital 08 Sep 2025 470.00 (4.17%) Buy 455.03
24 Jun 2025 360.00 (-20.21%) Buy 325.00
Citigroup 02 Sep 2025 583.00 (29.21%) Buy 447.00
11 Jul 2025 404.00 (-10.46%) Buy 314.94
HC Wainwright & Co. 02 Sep 2025 570.00 (26.33%) Buy 447.00
07 Aug 2025 570.00 (26.33%) Buy 435.10
JP Morgan 06 Aug 2025 475.00 (5.27%) Buy 428.14
16 Jul 2025 348.00 (-22.87%) Buy 322.81
Oppenheimer 04 Aug 2025 490.00 (8.60%) Buy 419.56
Barclays 01 Aug 2025 460.00 (1.95%) Buy 401.80
Canaccord Genuity 01 Aug 2025 415.00 (-8.02%) Buy 401.80
Chardan Capital 01 Aug 2025 400.00 (-11.35%) Buy 401.80
Morgan Stanley 01 Aug 2025 405.00 (-10.24%) Hold 401.80
Piper Sandler 01 Aug 2025 449.00 (-0.49%) Buy 401.80
Raymond James 01 Aug 2025 424.00 (-6.03%) Buy 401.80
Scotiabank 01 Aug 2025 450.00 (-0.27%) Buy 401.80
UBS 01 Aug 2025 550.00 (21.90%) Buy 401.80
Wells Fargo 01 Aug 2025 395.00 (-12.46%) Hold 401.80
30 Jun 2025 333.00 (-26.20%) Hold 326.09
Needham 31 Jul 2025 478.00 (5.94%) Buy 392.24
26 Jun 2025 377.00 (-16.45%) Buy 318.25
Truist Securities 21 Jul 2025 385.00 (-14.67%) Buy 320.52
Jefferies 07 Jul 2025 384.00 (-14.89%) Buy 324.13
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Name Avg. Buy ($) Avg. Sell ($) Net Quantity Net Value ($)
REITAN COLLEEN F - 482.13 -18,000 -8,678,340
Aggregate Net Quantity -18,000
Aggregate Net Value ($) -8,678,340
Aggregate Avg. Buy ($) -
Aggregate Avg. Sell ($) 482.13
Name Holder Date Type Quantity Price Value ($)
REITAN COLLEEN F Director 09 Sep 2025 Automatic sell (-) 18,000 482.13 8,678,340
REITAN COLLEEN F Director 09 Sep 2025 Option execute 18,000 - -

The support, resistance and trendline levels presented has been generated by an artificial intelligence (AI) model and should be interpreted with caution.

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