ANAPTYSBIO INC

NASDAQ: ANAB (AnaptysBio, Inc.)

Last update: 06 Jan, 3:22AM

43.20

-1.75 (-3.89%)

Previous Close 44.95
Open 44.66
Volume 452,062
Avg. Volume (3M) 508,980
Market Cap 1,208,433,536
Price / Sales 7.93
Price / Book 114.73
52 Weeks Range
12.21 (-71%) — 52.47 (21%)
Earnings Date 4 Nov 2025
Profit Margin -125.70%
Operating Margin (TTM) -99.16%
Diluted EPS (TTM) -4.76
Quarterly Revenue Growth (YOY) 286.80%
Total Debt/Equity (MRQ) 1,016.89%
Current Ratio (MRQ) 8.25
Operating Cash Flow (TTM) -108.78 M
Levered Free Cash Flow (TTM) -60.04 M
Return on Assets (TTM) -15.14%
Return on Equity (TTM) -343.83%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Bullish Mixed
Biotechnology (Global) Bullish Mixed
Stock AnaptysBio, Inc. Bullish Bullish

AIStockmoo Score

-0.4
Analyst Consensus 1.5
Insider Activity -3.5
Price Volatility -0.5
Technical Moving Averages 0.0
Technical Oscillators 0.5
Average -0.40

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AnaptysBio Inc is a clinical-stage biotechnology company. The company is focused on developing antibody product candidates for unmet medical needs in inflammation and immuno-oncology. The company is developing immune cell modulating antibodies, including two wholly owned checkpoint agonists in clinical-stage development, for autoimmune and inflammatory diseases; rosnilimab, our PD-1 agonist in a Phase 2b trial for the treatment of moderate-to-severe rheumatoid arthritis (RA) and a Phase 2 trial for the treatment of moderate-to-severe ulcerative colitis (UC); and ANB032, our BTLA agonist, in a Phase 2b trial for the treatment of moderate-to-severe atopic dermatitis (AD).

Sector Healthcare
Industry Biotechnology
Investment Style Small Core
% Held by Insiders 5.09%
% Held by Institutions 133.99%
52 Weeks Range
12.21 (-71%) — 52.47 (21%)
Price Target Range
36.00 (-16%) — 100.00 (131%)
High 100.00 (Guggenheim, 131.48%) Buy
Median 55.50 (28.47%)
Low 36.00 (Truist Securities, -16.67%) Hold
Average 62.38 (44.40%)
Total 7 Buy, 1 Hold
Avg. Price @ Call 40.82
Firm Date Target Price Call Price @ Call
UBS 07 Jan 2026 70.00 (62.04%) Buy 45.21
Barclays 17 Dec 2025 55.00 (27.31%) Buy 45.69
11 Nov 2025 70.00 (62.04%) Buy 33.56
Stifel 11 Dec 2025 56.00 (29.63%) Buy 45.78
29 Oct 2025 80.00 (85.19%) Buy 36.12
HC Wainwright & Co. 24 Nov 2025 51.00 (18.06%) Buy 41.95
11 Nov 2025 52.00 (20.37%) Buy 33.56
Wedbush 24 Nov 2025 50.00 (15.74%) Buy 41.95
Truist Securities 10 Nov 2025 36.00 (-16.67%) Hold 33.98
Guggenheim 05 Nov 2025 100.00 (131.48%) Buy 36.00
Wells Fargo 05 Nov 2025 81.00 (87.50%) Buy 36.00
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Name Avg. Buy ($) Avg. Sell ($) Net Quantity Net Value ($)
FAGA DANIEL - 44.07 -38,792 -1,702,879
LIZZUL PAUL F. - 44.07 -10,104 -443,175
LOUMEAU ERIC J - 44.36 -14,832 -661,443
MARQUET MAGDA - 46.31 -11,000 -509,410
MULROY DENNIS - 44.07 -7,786 -341,699
Aggregate Net Quantity -82,514
Aggregate Net Value ($) -3,658,606
Aggregate Avg. Buy ($) -
Aggregate Avg. Sell ($) 44.31
Name Holder Date Type Quantity Price Value ($)
MARQUET MAGDA Director 15 Jan 2026 Sell (-) 11,000 46.31 509,410
MARQUET MAGDA Director 15 Jan 2026 Option execute 11,000 - -
FAGA DANIEL Officer 08 Jan 2026 Sell (-) 14,281 43.80 625,508
LOUMEAU ERIC J Officer 08 Jan 2026 Sell (-) 2,210 43.80 96,798
MULROY DENNIS Officer 08 Jan 2026 Sell (-) 2,515 43.80 110,157
LIZZUL PAUL F. Officer 08 Jan 2026 Sell (-) 3,650 43.80 159,870
MULROY DENNIS Officer 07 Jan 2026 Sell (-) 1,908 45.21 86,261
FAGA DANIEL Officer 07 Jan 2026 Sell (-) 9,202 45.21 416,022
LIZZUL PAUL F. Officer 07 Jan 2026 Sell (-) 2,235 45.21 101,044
LOUMEAU ERIC J Officer 07 Jan 2026 Sell (-) 2,017 45.21 91,189
LOUMEAU ERIC J Officer 07 Jan 2026 Automatic sell (-) 7,622 45.21 344,591
FAGA DANIEL Officer 07 Jan 2026 Option execute 26,838 - -
LOUMEAU ERIC J Officer 07 Jan 2026 Option execute 5,888 - -
MULROY DENNIS Officer 07 Jan 2026 Option execute 6,700 - -
LIZZUL PAUL F. Officer 07 Jan 2026 Option execute 8,525 - -
MULROY DENNIS Officer 06 Jan 2026 Option execute 5,245 - -
FAGA DANIEL Officer 06 Jan 2026 Option execute 17,850 - -
LIZZUL PAUL F. Officer 06 Jan 2026 Option execute 6,145 - -
LOUMEAU ERIC J Officer 06 Jan 2026 Option execute 5,545 - -
LOUMEAU ERIC J Officer 05 Jan 2026 Sell (-) 2,983 43.20 128,866
LIZZUL PAUL F. Officer 05 Jan 2026 Sell (-) 4,219 43.20 182,261
MULROY DENNIS Officer 05 Jan 2026 Sell (-) 3,363 43.20 145,282
FAGA DANIEL Officer 05 Jan 2026 Sell (-) 15,309 43.20 661,349
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