ARROWHEAD PHARMACEUTICALS INC

NASDAQ: ARWR (Arrowhead Pharmaceuticals, Inc.)

Last update: 03 Jan, 1:01AM

67.79

1.40 (2.11%)

Previous Close 66.39
Open 66.30
Volume 1,103,696
Avg. Volume (3M) 2,329,601
Market Cap 9,372,479,488
Price / Earnings (Forward) 111.11
Price / Sales 10.56
Price / Book 19.58
52 Weeks Range
9.57 (-85%) — 72.36 (6%)
Earnings Date 9 Feb 2026
Profit Margin -26.41%
Operating Margin (TTM) 70.24%
Diluted EPS (TTM) -1.24
Quarterly Revenue Growth (YOY) -29.60%
Total Debt/Equity (MRQ) 108.23%
Current Ratio (MRQ) 5.15
Operating Cash Flow (TTM) 61.15 M
Levered Free Cash Flow (TTM) -6.46 M
Return on Assets (TTM) -5.86%
Return on Equity (TTM) -26.22%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Bullish Mixed
Biotechnology (Global) Bullish Mixed
Stock Arrowhead Pharmaceuticals, Inc. Bullish Bullish

AIStockmoo Score

-0.6
Analyst Consensus 4.0
Insider Activity -4.0
Price Volatility -5.0
Technical Moving Averages 2.5
Technical Oscillators -0.5
Average -0.60

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Arrowhead Pharmaceuticals Inc is an American biotechnology company. Its main target is the development of medicine to treat diseases with a genetic origin, characterized by the overproduction of one or more proteins. Its medical solutions are aimed at the genes that trigger the diseases. Its portfolio includes drugs targeting cardiovascular, Cardiometabolic, Central Nervous System, Pulmonary, Liver, Muscular, and Complement Mediated Disease. It majority products are liver disease curable.

Sector Healthcare
Industry Biotechnology
Investment Style Small Core
% Held by Insiders 13.02%
% Held by Institutions 77.19%
52 Weeks Range
9.57 (-85%) — 72.36 (6%)
Price Target Range
80.00 (18%) — 110.00 (62%)
High 110.00 (Piper Sandler, 62.27%) Buy
Median 81.00 (19.49%)
Low 80.00 (Chardan Capital, 18.01%) Buy
80.00 (RBC Capital, 18.01%) Buy
Average 86.00 (26.86%)
Total 5 Buy, 2 Hold
Avg. Price @ Call 65.75
Firm Date Target Price Call Price @ Call
Piper Sandler 13 Jan 2026 110.00 (62.27%) Buy 65.55
17 Dec 2025 100.00 (47.51%) Buy 64.80
Chardan Capital 07 Jan 2026 80.00 (18.01%) Buy 65.69
01 Dec 2025 60.00 (-11.49%) Buy 56.25
Goldman Sachs 07 Jan 2026 85.00 (25.39%) Hold 65.69
20 Nov 2025 48.00 (-29.19%) Hold 38.09
Morgan Stanley 07 Jan 2026 81.00 (19.49%) Hold 65.69
26 Nov 2025 48.00 (-29.19%) Hold 57.71
RBC Capital 11 Dec 2025 80.00 (18.01%) Buy 70.82
19 Nov 2025 52.00 (-23.29%) Buy 38.97
B of A Securities 09 Dec 2025 81.00 (19.49%) Buy 68.83
01 Dec 2025 62.00 (-8.54%) Buy 56.25
HC Wainwright & Co. 02 Dec 2025 85.00 (25.39%) Buy 57.95
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Name Avg. Buy ($) Avg. Sell ($) Net Quantity Net Value ($)
ANZALONE CHRISTOPHER RICHARD - 67.79 -13,187 -893,947
HAMILTON JAMES C - 63.88 -40,164 -2,565,676
O'BRIEN PATRICK - 63.88 -49,493 -3,161,613
Aggregate Net Quantity -102,844
Aggregate Net Value ($) -6,621,236
Aggregate Avg. Buy ($) -
Aggregate Avg. Sell ($) 65.18
Name Holder Date Type Quantity Price Value ($)
HAMILTON JAMES C Officer 05 Jan 2026 Automatic sell (-) 40,164 63.88 2,565,676
O'BRIEN PATRICK Officer 05 Jan 2026 Automatic sell (-) 49,493 63.88 3,161,613
ANZALONE CHRISTOPHER RICHARD Officer 02 Jan 2026 Automatic sell (-) 13,187 67.79 893,947
Date Type Details
07 Jan 2026 Announcement Arrowhead Pharmaceuticals Prices Upsized Offerings of Convertible Senior Notes, Common Stock and Pre-Funded Warrants
07 Jan 2026 Announcement Arrowhead Pharmaceuticals Announces NMPA Approval of REDEMPLO® (plozasiran) for Familial Chylomicronemia Syndrome (FCS) in China
06 Jan 2026 Announcement Arrowhead Pharmaceuticals Announces Proposed Offerings of Convertible Senior Notes and Common Stock
06 Jan 2026 Announcement Arrowhead Pharmaceuticals Announces Interim Clinical Data on RNAi-based Obesity Candidates Showing Weight Loss in Obese Patients with Diabetes and Improved Measures of Body Composition
05 Jan 2026 Announcement Arrowhead Pharmaceuticals Announces Health Canada Approval of REDEMPLO™ (plozasiran) to Reduce Triglycerides in Adults with Familial Chylomicronemia Syndrome (FCS)
23 Dec 2025 Announcement Arrowhead Pharmaceuticals to Participate in Upcoming January 2026 Events
15 Dec 2025 Announcement Arrowhead Pharmaceuticals Reports Inducement Grants under NASDAQ Listing Rule 5635(c)(4)
08 Dec 2025 Announcement Arrowhead Pharmaceuticals Initiates Phase 1/2a Study of ARO-MAPT for the Treatment of Alzheimer’s Disease and Other Tauopathies
02 Dec 2025 Announcement Arrowhead Pharmaceuticals Receives FDA Breakthrough Therapy Designation for Plozasiran in Severe Hypertriglyceridemia
01 Dec 2025 Announcement Arrowhead Pharmaceuticals to Participate in Upcoming December 2025 Conferences
25 Nov 2025 Announcement Arrowhead Pharmaceuticals Reports 2025 Fiscal Year-End Results
24 Nov 2025 Announcement Arrowhead Pharmaceuticals Earns $200 Million Milestone Payment from Sarepta Therapeutics
18 Nov 2025 Announcement Arrowhead Pharmaceuticals Announces FDA Approval of REDEMPLO® (plozasiran) to Reduce Triglycerides in Adults with Familial Chylomicronemia Syndrome (FCS)
06 Nov 2025 Announcement Arrowhead Pharmaceuticals to Webcast Fiscal 2025 Year-End Results
04 Nov 2025 Announcement Arrowhead Pharmaceuticals to Participate in Upcoming November 2025 Conferences
28 Oct 2025 Announcement Arrowhead Pharmaceuticals Reports Inducement Grants under NASDAQ Listing Rule 5635(c)(4)
21 Oct 2025 Announcement Arrowhead Pharmaceuticals Announces Closing of Global License and Collaboration Agreement with Novartis
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