AXSOME THERAPEUTICS INC

NASDAQ: AXSM (Axsome Therapeutics, Inc.)

Last update: 25 Nov, 2025, 10:30PM

150.36

-0.84 (-0.56%)

Previous Close 151.20
Open 152.13
Volume 359,541
Avg. Volume (3M) 542,834
Market Cap 7,580,044,800
Price / Earnings (Forward) 303.03
Price / Sales 15.51
Price / Book 120.91
52 Weeks Range
75.56 (-49%) — 152.94 (1%)
Earnings Date 3 Nov 2025
Profit Margin -64.39%
Operating Margin (TTM) -45.67%
Diluted EPS (TTM) -5.76
Quarterly Revenue Growth (YOY) 62.00%
Total Debt/Equity (MRQ) 397.02%
Current Ratio (MRQ) 2.03
Operating Cash Flow (TTM) -118.32 M
Levered Free Cash Flow (TTM) -20.98 M
Return on Assets (TTM) -26.17%
Return on Equity (TTM) -282.16%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Bullish Mixed
Biotechnology (Global) Bullish Mixed
Stock Axsome Therapeutics, Inc. Bullish Bullish

AIStockmoo Score

0.8
Analyst Consensus 4.0
Insider Activity -3.5
Price Volatility -0.5
Technical Moving Averages 0.0
Technical Oscillators 4.0
Average 0.80

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Axsome Therapeutics Inc is a clinical-stage biopharmaceutical company. It is engaged in developing novel therapies for the management of the central nervous system, or CNS, disorders for which there are limited treatment options. Its pipeline products includes AXS-05, AXS-07, AXS-12, and AXS-14. It manages its business as one operating segment and reporting unit, which is the business of developing and delivering novel therapies for the management of CNS disorders.

Sector Healthcare
Industry Biotechnology
Investment Style Small Growth
% Held by Insiders 16.31%
% Held by Institutions 76.41%
52 Weeks Range
75.56 (-49%) — 152.94 (1%)
Price Target Range
169.00 (12%) — 248.00 (64%)
High 248.00 (UBS, 64.94%) Buy
Median 201.00 (33.68%)
Low 169.00 (Needham, 12.40%) Buy
Average 202.38 (34.60%)
Total 7 Buy, 1 Hold
Avg. Price @ Call 159.73
Firm Date Target Price Call Price @ Call
Wells Fargo 13 Jan 2026 193.00 (28.36%) Buy 174.98
04 Nov 2025 157.00 (4.42%) Buy 134.93
Morgan Stanley 08 Jan 2026 204.00 (35.67%) Hold 167.55
04 Nov 2025 196.00 (30.35%) Buy 134.93
UBS 06 Jan 2026 248.00 (64.94%) Buy 171.88
HC Wainwright & Co. 05 Jan 2026 200.00 (33.01%) Buy 171.49
04 Nov 2025 185.00 (23.04%) Buy 134.93
Needham 31 Dec 2025 169.00 (12.40%) Buy 182.64
04 Nov 2025 154.00 (2.42%) Buy 134.93
Mizuho 06 Nov 2025 202.00 (34.34%) Buy 139.41
Guggenheim 04 Nov 2025 205.00 (36.34%) Buy 134.93
RBC Capital 04 Nov 2025 198.00 (31.68%) Buy 134.93
Show more
Name Avg. Buy ($) Avg. Sell ($) Net Quantity Net Value ($)
SAAD MARK E - 182.64 -37,577 -6,863,063
TABUTEAU HERRIOT - 171.35 -139,414 -23,894,584
Aggregate Net Quantity -176,991
Aggregate Net Value ($) -30,757,647
Aggregate Avg. Buy ($) -
Aggregate Avg. Sell ($) 174.18
Name Holder Date Type Quantity Price Value ($)
TABUTEAU HERRIOT Officer 07 Jan 2026 Automatic sell (-) 31,261 170.69 5,335,940
TABUTEAU HERRIOT Officer 07 Jan 2026 Option execute 31,261 - -
TABUTEAU HERRIOT Officer 06 Jan 2026 Automatic sell (-) 29,450 171.88 5,061,866
TABUTEAU HERRIOT Officer 06 Jan 2026 Option execute 29,450 - -
TABUTEAU HERRIOT Officer 05 Jan 2026 Automatic sell (-) 78,703 171.49 13,496,777
TABUTEAU HERRIOT Officer 05 Jan 2026 Option execute 78,703 - -
SAAD MARK E Director 31 Dec 2025 Automatic sell (-) 37,577 182.64 6,863,063
SAAD MARK E Director 31 Dec 2025 Option execute 37,577 - -

The support, resistance and trendline levels presented has been generated by an artificial intelligence (AI) model and should be interpreted with caution.

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