IONIS PHARMACEUTICALS INC

NASDAQ: IONS (Ionis Pharmaceuticals, Inc.)

Last update: 08 Jun, 11:27AM

35.29

0.05 (0.14%)

Previous Close 35.24
Open 35.59
Volume 1,197,322
Avg. Volume (3M) 1,651,300
Market Cap 5,616,721,408
Price / Earnings (Forward) 90.91
Price / Sales 8.42
Price / Book 13.22
52 Weeks Range
23.95 (-32%) — 52.34 (48%)
Earnings Date 30 Jul 2025 - 4 Aug 2025
Profit Margin -63.86%
Operating Margin (TTM) -111.59%
Diluted EPS (TTM) -2.99
Quarterly Revenue Growth (YOY) 10.10%
Total Debt/Equity (MRQ) 413.80%
Current Ratio (MRQ) 9.66
Operating Cash Flow (TTM) -501.78 M
Levered Free Cash Flow (TTM) -368.16 M
Return on Assets (TTM) -10.59%
Return on Equity (TTM) -118.62%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Bearish Bearish
Biotechnology (Global) Bearish Bearish
Stock Ionis Pharmaceuticals, Inc. Bullish Bearish

AIStockmoo Score

0.6
Analyst Consensus 4.0
Insider Activity NA
Price Volatility -2.0
Technical Moving Averages -1.5
Technical Oscillators 2.0
Average 0.63

Similar Stocks

Stock Market Cap DY P/E (TTM) P/B
IONS 6 B - - 13.22
CRNX 3 B - - 2.12
IRON 2 B - - 2.68
HRMY 2 B - 12.16 2.56
NVAX 1 B - 2.47 -
CDTX 1 B - - 7.20

Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis received FDA approval in 2024 for Tryngolza for a rare high-triglyceride syndrome, marking its first independent launch.

Sector Healthcare
Industry Biotechnology
Investment Style Small Core
% Held by Insiders 0.84%
% Held by Institutions 108.34%

Ownership

Name Date Shares Held
Tweedy, Browne Co Llc 31 Dec 2024 3,248,863
52 Weeks Range
23.95 (-32%) — 52.34 (48%)
Price Target Range
48.00 (36%) — 64.00 (81%)
High 64.00 (Guggenheim, 81.35%) Buy
Median 55.00 (55.85%)
Low 48.00 (JP Morgan, 36.02%) Hold
Average 54.80 (55.29%)
Total 4 Buy, 1 Hold
Avg. Price @ Call 35.47
Firm Date Target Price Call Price @ Call
Barclays 01 Jul 2025 57.00 (61.52%) Buy 39.51
HC Wainwright & Co. 26 Jun 2025 50.00 (41.68%) Buy 39.78
20 May 2025 50.00 (41.68%) Buy 34.47
JP Morgan 12 Jun 2025 48.00 (36.02%) Hold 35.62
Guggenheim 01 May 2025 64.00 (81.35%) Buy 31.71
Needham 30 Apr 2025 55.00 (55.85%) Buy 30.71
15 Apr 2025 60.00 (70.02%) Buy 28.38

No data within this time range.

The support, resistance and trendline levels presented has been generated by an artificial intelligence (AI) model and should be interpreted with caution.

Portfolio

AI Template

Your price alert

Risk Profile

| | | | |
Conservative
Moderate Conservative
Moderate
Moderate Aggressive
Aggressive
Margin of Safety (EP)
Partial Profit (TP1)
Target Profit (TP2)
Maximum Loss (SL)

Disclaimer: The above is for illustrative purposes only and is NOT investment advice. Seek advice from a qualified financial professional.

Entry Price (EP)

Take Profit 1 (TP1)

Take Profit 2 (TP2)

Stop Loss (SL)

52W Range
 
52WL
 
52WH
SL
EP
TP1
TP2

All alert prices are within 52 weeks price range

Realized Profit -
Unrealized Profit -
Dividend Received 2025 -
Total Profit -
Avg. Return -
Quantity (Buy) -
Avg. Price (Buy) -
Quantity (Sold) -
Avg. Price (Sold) -
No stocks matching your criteria