IONIS PHARMACEUTICALS INC

NASDAQ: IONS (Ionis Pharmaceuticals, Inc.)

Last update: 13 hours ago

54.39

-0.26 (-0.48%)

Previous Close 54.65
Open 54.10
Volume 2,547,051
Avg. Volume (3M) 2,534,582
Market Cap 8,988,631,040
Price / Earnings (Forward) 90.91
Price / Sales 8.30
Price / Book 18.29
52 Weeks Range
40.03 (-26%) — 86.74 (59%)
Earnings Date 29 Jul 2026
Profit Margin -63.86%
Operating Margin (TTM) -111.59%
Diluted EPS (TTM) -2.99
Quarterly Revenue Growth (YOY) 10.10%
Total Debt/Equity (MRQ) 413.80%
Current Ratio (MRQ) 9.66
Operating Cash Flow (TTM) -501.78 M
Levered Free Cash Flow (TTM) -368.16 M
Return on Assets (TTM) -10.59%
Return on Equity (TTM) -118.62%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Mixed Bullish
Biotechnology (Global) Mixed Bullish
Stock Ionis Pharmaceuticals, Inc. Mixed Bullish

AIStockmoo Score

0.4
Analyst Consensus NA
Insider Activity 0.0
Price Volatility 4.5
Technical Moving Averages -2.5
Technical Oscillators -0.5
Average 0.38

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Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis received FDA approval in 2024 for Tryngolza for a rare high-triglyceride syndrome, marking its first independent launch.

Sector Healthcare
Industry Biotechnology
Investment Style Small Core
% Held by Insiders 0.83%
% Held by Institutions 108.17%

No data within this time range.

Name Avg. Buy ($) Avg. Sell ($) Net Quantity Net Value ($)
BENNETT C FRANK 86.33 86.33 -5,536 -477,923
DIAZ ALLENE M. - 86.33 -10,111 -872,883
KORDASIEWICZ HOLLY B. - 86.33 -362 -31,251
Aggregate Net Quantity -16,009
Aggregate Net Value ($) -1,382,057
Aggregate Avg. Buy ($) 86.33
Aggregate Avg. Sell ($) 86.33
Name Holder Date Type Quantity Price Value ($)
KORDASIEWICZ HOLLY B. Officer 07 Jul 2026 Automatic sell (-) 362 86.33 31,251
DIAZ ALLENE M. Director 07 Jul 2026 Automatic sell (-) 10,111 86.33 872,883
DIAZ ALLENE M. Director 07 Jul 2026 Option execute 10,111 - -
BENNETT C FRANK Officer 07 Jul 2026 Automatic sell (-) 5,536 86.33 477,923
BENNETT C FRANK Officer 07 Jul 2026 Acquired (+) 15,000 86.33 1,294,950
BENNETT C FRANK Officer 07 Jul 2026 Automatic sell (-) 15,000 86.33 1,294,950

The support, resistance and trendline levels presented has been generated by an artificial intelligence (AI) model and should be interpreted with caution.

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