IONIS PHARMACEUTICALS INC

NASDAQ: IONS (Ionis Pharmaceuticals, Inc.)

Last update: 2 days ago, 11:11AM

75.72

1.60 (2.16%)

Previous Close 74.12
Open 74.85
Volume 550,600
Avg. Volume (3M) 1,814,454
Market Cap 12,513,681,408
Price / Earnings (Forward) 90.91
Price / Sales 11.16
Price / Book 24.58
52 Weeks Range
36.93 (-51%) — 86.74 (14%)
Earnings Date 5 Aug 2026
Profit Margin -63.86%
Operating Margin (TTM) -111.59%
Diluted EPS (TTM) -2.99
Quarterly Revenue Growth (YOY) 10.10%
Total Debt/Equity (MRQ) 413.80%
Current Ratio (MRQ) 9.66
Operating Cash Flow (TTM) -501.78 M
Levered Free Cash Flow (TTM) -368.16 M
Return on Assets (TTM) -10.59%
Return on Equity (TTM) -118.62%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Bullish Mixed
Biotechnology (Global) Bullish Mixed
Stock Ionis Pharmaceuticals, Inc. Bullish Bullish

AIStockmoo Score

0.5
Analyst Consensus 2.0
Insider Activity NA
Price Volatility 2.0
Technical Moving Averages 0.0
Technical Oscillators -2.0
Average 0.50

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Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis received FDA approval in 2024 for Tryngolza for a rare high-triglyceride syndrome, marking its first independent launch.

Sector Healthcare
Industry Biotechnology
Investment Style Small Core
% Held by Insiders 0.83%
% Held by Institutions 108.17%

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The support, resistance and trendline levels presented has been generated by an artificial intelligence (AI) model and should be interpreted with caution.

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