PROTAGONIST THERAPEUTICS INC

NASDAQ: PTGX (Protagonist Therapeutics, Inc.)

Last update: 6 days ago, 11:44PM

81.76

-1.32 (-1.59%)

Previous Close 83.08
Open 82.45
Volume 771,447
Avg. Volume (3M) 900,188
Market Cap 5,111,280,640
Price / Earnings (TTM) 123.88
Price / Earnings (Forward) 26.39
Price / Sales 24.46
Price / Book 7.72
52 Weeks Range
33.70 (-58%) — 96.54 (18%)
Earnings Date 6 Nov 2025
Profit Margin 27.04%
Operating Margin (TTM) -68.18%
Diluted EPS (TTM) 0.780
Quarterly Revenue Growth (YOY) -88.90%
Quarterly Earnings Growth (YOY) 381.70%
Total Debt/Equity (MRQ) 1.65%
Current Ratio (MRQ) 17.25
Operating Cash Flow (TTM) 336.94 M
Levered Free Cash Flow (TTM) 327.76 M
Return on Assets (TTM) 2.48%
Return on Equity (TTM) 8.99%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Bullish Mixed
Biotechnology (Global) Bullish Mixed
Stock Protagonist Therapeutics, Inc. Bullish Bullish

AIStockmoo Score

-1.1
Analyst Consensus 1.5
Insider Activity -3.5
Price Volatility -0.5
Technical Moving Averages -2.5
Technical Oscillators -0.5
Average -1.10

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ACAD 4 B - 16.08 4.74
CORT 4 B - 51.12 7.32
ADMA 4 B - 20.37 9.60

Protagonist Therapeutics Inc is a clinical-stage biopharmaceutical company having a proprietary technology platform that enables the discovery and development of novel constrained peptide-based drug candidates to address medical needs. Its pipeline products include Rusfertide (PTG-300) and JNJ-2113.

Sector Healthcare
Industry Biotechnology
Investment Style Small Growth
% Held by Insiders 1.10%
% Held by Institutions 108.49%
52 Weeks Range
33.70 (-58%) — 96.54 (18%)
Price Target Range
81.00 (-0%) — 117.00 (43%)
High 117.00 (HC Wainwright & Co., 43.10%) Buy
Median 109.00 (33.32%)
Low 81.00 (JP Morgan, -0.93%) Buy
Average 105.50 (29.04%)
Total 6 Buy
Avg. Price @ Call 84.11
Firm Date Target Price Call Price @ Call
HC Wainwright & Co. 30 Jan 2026 117.00 (43.10%) Buy 81.80
Truist Securities 05 Jan 2026 110.00 (34.54%) Buy 84.18
Barclays 17 Dec 2025 108.00 (32.09%) Buy 89.34
07 Nov 2025 88.00 (7.63%) Buy 79.54
Citigroup 08 Dec 2025 115.00 (40.66%) Buy 90.25
10 Nov 2025 98.00 (19.86%) Buy 83.23
Citizens 07 Nov 2025 102.00 (24.76%) Buy 79.54
JP Morgan 07 Nov 2025 81.00 (-0.93%) Buy 79.54
Name Avg. Buy ($) Avg. Sell ($) Net Quantity Net Value ($)
ALI ASIF - 83.08 -46,203 -3,838,545
MOLINA ARTURO MD - 82.83 -23,151 -1,919,748
PATEL DINESH V PH D - 82.90 -54,273 -4,490,093
Aggregate Net Quantity -123,627
Aggregate Net Value ($) -10,248,386
Aggregate Avg. Buy ($) -
Aggregate Avg. Sell ($) 82.89
Name Holder Date Type Quantity Price Value ($)
MOLINA ARTURO MD Officer 27 Jan 2026 Sell (-) 5,000 83.08 415,400
MOLINA ARTURO MD Officer 27 Jan 2026 Option execute 5,000 - -
ALI ASIF Officer 27 Jan 2026 Sell (-) 46,203 83.08 3,838,545
ALI ASIF Officer 27 Jan 2026 Option execute 28,000 - -
PATEL DINESH V PH D Officer 27 Jan 2026 Sell (-) 4,068 83.08 337,969
PATEL DINESH V PH D Officer 27 Jan 2026 Option execute 4,068 - -
MOLINA ARTURO MD Officer 26 Jan 2026 Sell (-) 5,000 82.30 411,500
MOLINA ARTURO MD Officer 26 Jan 2026 Option execute 5,000 - -
PATEL DINESH V PH D Officer 26 Jan 2026 Sell (-) 24,890 82.30 2,048,447
PATEL DINESH V PH D Officer 26 Jan 2026 Option execute 24,890 - -
MOLINA ARTURO MD Officer 23 Jan 2026 Sell (-) 13,151 83.10 1,092,848
PATEL DINESH V PH D Officer 23 Jan 2026 Disposed (-) 6,000 83.10 498,600
PATEL DINESH V PH D Officer 23 Jan 2026 Sell (-) 19,315 83.10 1,605,077
PATEL DINESH V PH D Officer 23 Jan 2026 Option execute 19,315 - -
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The support, resistance and trendline levels presented has been generated by an artificial intelligence (AI) model and should be interpreted with caution.

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