ULTRAGENYX

NASDAQ: RARE (Ultragenyx Pharmaceutical Inc.)

Last update: 2 hours ago

21.34

-0.37 (-1.70%)

Previous Close 21.71
Open 21.94
Volume 2,542,744
Avg. Volume (3M) 2,815,493
Market Cap 2,062,079,744
Price / Sales 3.35
Price / Book 247.70
52 Weeks Range
18.41 (-13%) — 42.37 (98%)
Earnings Date 5 May 2026
Profit Margin -93.04%
Operating Margin (TTM) -102.62%
Diluted EPS (TTM) -5.83
Quarterly Revenue Growth (YOY) 28.00%
Total Debt/Equity (MRQ) 588.24%
Current Ratio (MRQ) 2.40
Operating Cash Flow (TTM) -389.94 M
Levered Free Cash Flow (TTM) -172.94 M
Return on Assets (TTM) -24.51%
Return on Equity (TTM) -377.06%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Bullish Mixed
Biotechnology (Global) Bullish Mixed
Stock Ultragenyx Pharmaceutical Inc. Bearish Bearish

AIStockmoo Score

1.7
Analyst Consensus 4.0
Insider Activity 1.0
Price Volatility 0.5
Technical Moving Averages 3.5
Technical Oscillators -0.5
Average 1.70

Similar Stocks

Stock Market Cap DY P/E (TTM) P/B
RARE 2 B - - 247.70
NUVL 7 B - - 6.31
CRNX 4 B - - 3.89
IDYA 3 B - - 2.82
AUPH 2 B - 7.15 5.11
NVAX 2 B - 3.97 33.20

Ultragenyx Pharmaceutical Inc is a USA-based biopharmaceutical company. It identifies, acquires, develops, and commercializes novel products for the treatment of serious rare and ultra-rare diseases, with a focus on serious, debilitating genetic diseases. The company's medicine portfolio includes Crysvita, Dojolvi and Mepsevii. Crysvita is indicated for the treatment of X-linked hypophosphatemia (XLH) in adult and pediatric patients 1 year of age and older. Mepsevii is indicated in pediatric and adult patients for the treatment of Mucopolysaccharidosis VII.

Sector Healthcare
Industry Biotechnology
Investment Style Small Core
% Held by Insiders 3.20%
% Held by Institutions 99.43%

Ownership

Name Date Shares Held
Sands Capital Management, Llc 31 Dec 2025 3,485,724
Rtw Investments, Lp 31 Dec 2025 3,000,139
Baker Bros. Advisors Lp 31 Dec 2025 2,772,692
Frontier Capital Management Co Llc 31 Dec 2025 1,965,084
Bnp Paribas Asset Management Holding S.A. 31 Dec 2025 1,899,661
52 Weeks Range
18.41 (-13%) — 42.37 (98%)
Price Target Range
25.00 (17%) — 79.00 (270%)
High 79.00 (Canaccord Genuity, 270.20%) Buy
Median 51.00 (138.99%)
Low 25.00 (Wedbush, 17.15%) Hold
Average 52.30 (145.08%)
Total 9 Buy, 1 Hold
Avg. Price @ Call 21.91
Firm Date Target Price Call Price @ Call
Canaccord Genuity 18 Feb 2026 79.00 (270.20%) Buy 20.45
Evercore ISI Group 18 Feb 2026 34.00 (59.33%) Buy 20.45
17 Feb 2026 37.00 (73.38%) Buy 20.18
HC Wainwright & Co. 17 Feb 2026 50.00 (134.30%) Buy 20.18
03 Feb 2026 60.00 (181.16%) Buy 24.80
Wedbush 17 Feb 2026 25.00 (17.15%) Hold 20.18
Guggenheim 05 Jan 2026 52.00 (143.67%) Buy 23.11
B of A Securities 02 Jan 2026 58.00 (171.79%) Buy 23.60
Baird 30 Dec 2025 47.00 (120.24%) Buy 22.78
Jefferies 30 Dec 2025 63.00 (195.22%) Buy 22.78
Leerink Partners 30 Dec 2025 70.00 (228.02%) Buy 22.78
Wells Fargo 30 Dec 2025 45.00 (110.87%) Buy 22.78
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Name Avg. Buy ($) Avg. Sell ($) Net Quantity Net Value ($)
CROMBEZ ERIC 23.39 23.02 4,614 110,522
HARRIS ERIK 23.39 23.02 1,104 29,722
HORN HOWARD 23.39 22.55 -3,901 -85,975
HUANG DENNIS KARL 23.39 23.02 10,138 237,497
HUIZENGA THEODORE ALAN - 23.02 -1,780 -40,976
KAKKIS EMIL D 23.39 23.02 16,773 412,450
PARSCHAUER KARAH HERDMAN 23.39 22.37 -6,524 -134,778
PINION JOHN RICHARD 23.39 23.02 1,108 29,627
Aggregate Net Quantity 21,532
Aggregate Net Value ($) 558,089
Aggregate Avg. Buy ($) 23.39
Aggregate Avg. Sell ($) 22.78
Name Holder Date Type Quantity Price Value ($)
PARSCHAUER KARAH HERDMAN Officer 10 Mar 2026 Sell (-) 3,508 22.84 80,123
PARSCHAUER KARAH HERDMAN Officer 06 Mar 2026 Sell (-) 6,018 21.25 127,883
HORN HOWARD Officer 03 Mar 2026 Sell (-) 1,635 22.07 36,084
HUANG DENNIS KARL Officer 02 Mar 2026 Disposed (-) 999 23.02 22,997
CROMBEZ ERIC Officer 02 Mar 2026 Sell (-) 7,029 23.02 161,808
HORN HOWARD Officer 02 Mar 2026 Sell (-) 8,409 23.02 193,575
HUIZENGA THEODORE ALAN Officer 02 Mar 2026 Disposed (-) 148 23.02 3,407
HUIZENGA THEODORE ALAN Officer 02 Mar 2026 Sell (-) 1,632 23.02 37,569
PARSCHAUER KARAH HERDMAN Officer 02 Mar 2026 Sell (-) 8,135 23.02 187,268
KAKKIS EMIL D Officer 02 Mar 2026 Sell (-) 54,404 23.02 1,252,380
HARRIS ERIK Officer 02 Mar 2026 Sell (-) 10,539 23.02 242,608
PINION JOHN RICHARD Officer 02 Mar 2026 Sell (-) 10,029 23.02 230,868
HUANG DENNIS KARL Officer 01 Mar 2026 Acquired (+) 11,137 23.39 260,494
CROMBEZ ERIC Officer 01 Mar 2026 Acquired (+) 11,643 23.39 272,330
HORN HOWARD Officer 01 Mar 2026 Acquired (+) 6,143 23.39 143,685
PARSCHAUER KARAH HERDMAN Officer 01 Mar 2026 Acquired (+) 11,137 23.39 260,494
KAKKIS EMIL D Officer 01 Mar 2026 Acquired (+) 71,177 23.39 1,664,830
HARRIS ERIK Officer 01 Mar 2026 Acquired (+) 11,643 23.39 272,330
PINION JOHN RICHARD Officer 01 Mar 2026 Acquired (+) 11,137 23.39 260,494
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