SEPTERNA, INC. COMMON STOCK

NASDAQ: SEPN (Septerna, Inc.)

Last update: 6 days ago, 9:32AM

26.77

0.39 (1.48%)

Previous Close 26.38
Open 24.84
Volume 9,355
Avg. Volume (3M) 318,150
Market Cap 1,198,605,184
Price / Earnings (Forward) 104.17
Price / Sales 52.79
Price / Book 3.00
52 Weeks Range
4.17 (-84%) — 30.50 (13%)
Earnings Date 10 Nov 2025
Operating Margin (TTM) -11,831.05%
Diluted EPS (TTM) -1.78
Quarterly Revenue Growth (YOY) -30.90%
Total Debt/Equity (MRQ) 6.25%
Current Ratio (MRQ) 32.19
Operating Cash Flow (TTM) -74.10 M
Levered Free Cash Flow (TTM) -25.69 M
Return on Assets (TTM) -17.20%
Return on Equity (TTM) -30.96%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Bullish Mixed
Biotechnology (Global) Bullish Mixed
Stock Septerna, Inc. Bullish Bearish

AIStockmoo Score

0.8
Analyst Consensus 4.0
Insider Activity NA
Price Volatility -0.5
Technical Moving Averages 0.0
Technical Oscillators -0.5
Average 0.75

Similar Stocks

Stock Market Cap DY P/E (TTM) P/B
SEPN 1 B - - 3.00
ASND 13 B - - -
MBX 2 B - 5.28 3.67
IMCR 2 B - - 4.12
PVLA 1 B - - 30.91
ZBIO 1 B - 1.53 5.51

Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, and GLP-1R, GIPR, GCGR.

Sector Healthcare
Industry Biotechnology
% Held by Insiders 2.64%
% Held by Institutions 105.46%

Ownership

Name Date Shares Held
Trv Gp V, Llc 30 Sep 2025 6,215,591
Trv Gp Vi, Llc 30 Sep 2025 4,211,659
52 Weeks Range
4.17 (-84%) — 30.50 (13%)
Price Target Range
28.00 (4%) — 43.00 (60%)
High 43.00 (Jones Trading, 60.63%) Buy
Median 34.00 (27.01%)
Low 28.00 (Wells Fargo, 4.60%) Buy
Average 34.60 (29.25%)
Total 5 Buy
Avg. Price @ Call 25.50
Firm Date Target Price Call Price @ Call
Jones Trading 23 Dec 2025 43.00 (60.63%) Buy 28.23
Raymond James 19 Dec 2025 38.00 (41.95%) Buy 29.58
Truist Securities 15 Dec 2025 34.00 (27.01%) Buy 27.18
Wells Fargo 14 Nov 2025 28.00 (4.59%) Buy 23.27
HC Wainwright & Co. 11 Nov 2025 30.00 (12.07%) Buy 19.24

No data within this time range.

The support, resistance and trendline levels presented has been generated by an artificial intelligence (AI) model and should be interpreted with caution.

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