SEPTERNA, INC. COMMON STOCK

NASDAQ: SEPN (Septerna, Inc.)

Last update: 01 Feb, 8:56AM

23.34

-0.46 (-1.93%)

Previous Close 23.80
Open 23.40
Volume 278,159
Avg. Volume (3M) 311,221
Market Cap 1,045,029,632
Price / Sales 53.98
Price / Book 3.07
52 Weeks Range
4.17 (-82%) — 30.50 (30%)
Earnings Date 10 Nov 2025
Operating Margin (TTM) -11,831.05%
Diluted EPS (TTM) -1.78
Quarterly Revenue Growth (YOY) -30.90%
Total Debt/Equity (MRQ) 6.25%
Current Ratio (MRQ) 32.19
Operating Cash Flow (TTM) -74.10 M
Levered Free Cash Flow (TTM) -25.69 M
Return on Assets (TTM) -17.20%
Return on Equity (TTM) -30.96%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Bullish Mixed
Biotechnology (Global) Bullish Mixed
Stock Septerna, Inc. Bullish Bullish

AIStockmoo Score

-0.1
Analyst Consensus 3.0
Insider Activity NA
Price Volatility -1.5
Technical Moving Averages 0.0
Technical Oscillators -2.0
Average -0.13

Similar Stocks

Stock Market Cap DY P/E (TTM) P/B
SEPN 1 B - - 3.07
BNTX 27 B - - 1.25
GPCR 5 B - - 7.45
CNTA 4 B - - 11.51
LEGN 3 B - - 3.39
ALMS 3 B - - 8.49

Septerna Inc is a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) oral small molecule drug discovery powered by a proprietary Native Complex Platform. Its industrial-scale platform aims to unlock the full potential of GPCR therapies. The group discovery and development of a pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic disease. Its pipeline includes SEP-786 (PTH1R), SEP-631 (MRGPRX2), TSHR, and GLP-1R, GIPR, GCGR.

Sector Healthcare
Industry Biotechnology
% Held by Insiders 2.64%
% Held by Institutions 105.46%
52 Weeks Range
4.17 (-82%) — 30.50 (30%)
Price Target Range
28.00 (19%) — 43.00 (84%)
High 43.00 (Jones Trading, 84.23%) Buy
Median 35.00 (49.96%)
Low 28.00 (Wells Fargo, 19.97%) Buy
Average 35.60 (52.53%)
Total 5 Buy
Avg. Price @ Call 27.06
Firm Date Target Price Call Price @ Call
HC Wainwright & Co. 20 Jan 2026 35.00 (49.96%) Buy 27.03
Jones Trading 23 Dec 2025 43.00 (84.23%) Buy 28.23
Raymond James 19 Dec 2025 38.00 (62.81%) Buy 29.58
Truist Securities 15 Dec 2025 34.00 (45.67%) Buy 27.18
Wells Fargo 14 Nov 2025 28.00 (19.97%) Buy 23.27

No data within this time range.

The support, resistance and trendline levels presented has been generated by an artificial intelligence (AI) model and should be interpreted with caution.

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