SPYRE THERAPEUTICS INC.

NASDAQ: SYRE (Spyre Therapeutics, Inc.)

Last update: 16 Feb, 11:28PM

36.63

1.79 (5.14%)

Previous Close 34.84
Open 35.02
Volume 1,320,217
Avg. Volume (3M) 710,798
Market Cap 2,842,199,808
Price / Sales 650.22
Price / Book 5.79
52 Weeks Range
10.91 (-70%) — 37.98 (3%)
Earnings Date 19 Feb 2026
Diluted EPS (TTM) -3.06
Total Debt/Equity (MRQ) 0.06%
Current Ratio (MRQ) 8.06
Operating Cash Flow (TTM) -169.86 M
Levered Free Cash Flow (TTM) -68.57 M
Return on Assets (TTM) -25.34%
Return on Equity (TTM) -65.82%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Bullish Mixed
Biotechnology (Global) Bullish Mixed
Stock Spyre Therapeutics, Inc. Bearish Bearish

AIStockmoo Score

-1.0
Analyst Consensus 1.0
Insider Activity NA
Price Volatility -4.5
Technical Moving Averages -2.5
Technical Oscillators 2.0
Average -1.00

Similar Stocks

Stock Market Cap DY P/E (TTM) P/B
SYRE 3 B - - 5.79
MRNA 20 B - - 2.46
CELC 5 B - - 44.51
HRMY 2 B - 10.27 1.84
MNMD 1 B - - 5.42
VIR 1 B - - 1.90

Spyre Therapeutics Inc is a biotechnology company that aims to create the next-generation of inflammatory bowel disease (IBD) products by combining antibody engineering, rational therapeutic combinations, and precision medicine approaches for patient selection. IBD is a chronic condition characterized by inflammation within the gastrointestinal tract, including two main disorders which are UC and CD. It has a single reportable segment, which is the development of biopharmaceutical products for the treatment of patients with IBD and other immune-mediated disease.

Sector Healthcare
Industry Biotechnology
Investment Style Small Value
% Held by Insiders 8.71%
% Held by Institutions 106.07%
52 Weeks Range
10.91 (-70%) — 37.98 (3%)
Price Target Range
50.00 (36%) — 70.00 (91%)
High 70.00 (BTIG, 91.10%) Buy
Median 60.00 (63.80%)
Low 50.00 (Wells Fargo, 36.50%) Buy
Average 60.00 (63.80%)
Total 2 Buy
Avg. Price @ Call 43.21
Firm Date Target Price Call Price @ Call
BTIG 20 Feb 2026 70.00 (91.10%) Buy 43.21
16 Jan 2026 70.00 (91.10%) Buy 33.24
Wells Fargo 20 Feb 2026 50.00 (36.50%) Buy 43.21

No data within this time range.

The support, resistance and trendline levels presented has been generated by an artificial intelligence (AI) model and should be interpreted with caution.

Portfolio

AI Template

Your price alert

Risk Profile

| | | | |
Conservative
Moderate Conservative
Moderate
Moderate Aggressive
Aggressive
Margin of Safety (EP)
Partial Profit (TP1)
Target Profit (TP2)
Maximum Loss (SL)

Disclaimer: The above is for illustrative purposes only and is NOT investment advice. Seek advice from a qualified financial professional.

Entry Price (EP)

Take Profit 1 (TP1)

Take Profit 2 (TP2)

Stop Loss (SL)

52W Range
 
52WL
 
52WH
SL
EP
TP1
TP2

All alert prices are within 52 weeks price range

Realized Profit -
Unrealized Profit -
Dividend Received 2026 -
Total Profit -
Avg. Return -
Quantity (Buy) -
Avg. Price (Buy) -
Quantity (Sold) -
Avg. Price (Sold) -
No stocks matching your criteria