SPYRE THERAPEUTICS INC.

NASDAQ: SYRE (Spyre Therapeutics, Inc.)

Last update: 12 Sep, 11:15PM

15.65

-0.55 (-3.40%)

Previous Close 16.20
Open 16.11
Volume 420,414
Avg. Volume (3M) 549,430
Market Cap 945,275,648
Price / Sales 650.22
Price / Book 3.22
52 Weeks Range
10.91 (-30%) — 40.26 (157%)
Earnings Date 6 Nov 2025
Diluted EPS (TTM) -3.06
Total Debt/Equity (MRQ) 0.06%
Current Ratio (MRQ) 8.06
Operating Cash Flow (TTM) -169.86 M
Levered Free Cash Flow (TTM) -68.57 M
Return on Assets (TTM) -25.34%
Return on Equity (TTM) -65.82%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Mixed Mixed
Biotechnology (Global) Mixed Mixed
Stock Spyre Therapeutics, Inc. Bullish Bullish

AIStockmoo Score

1.3
Analyst Consensus 5.0
Insider Activity NA
Price Volatility -2.0
Technical Moving Averages 0.0
Technical Oscillators 2.0
Average 1.25

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Spyre Therapeutics Inc is a biotechnology company that aims to create the next-generation of inflammatory bowel disease (IBD) products by combining antibody engineering, rational therapeutic combinations, and precision medicine approaches for patient selection. IBD is a chronic condition characterized by inflammation within the gastrointestinal tract, including two main disorders which are UC and CD. A range of pharmaceutical options to address IBD exists, including anti-inflammatory drugs, immunosuppressants, and biologics.

Sector Healthcare
Industry Biotechnology
Investment Style Small Value
% Held by Insiders 8.71%
% Held by Institutions 106.07%
52 Weeks Range
10.91 (-30%) — 40.26 (157%)
Price Target Range
43.00 (174%) — 70.00 (347%)
High 70.00 (BTIG, 347.28%) Buy
Median 56.50 (261.02%)
Low 43.00 (Deutsche Bank, 174.76%) Buy
Average 56.50 (261.02%)
Total 2 Buy
Avg. Price @ Call 15.53
Firm Date Target Price Call Price @ Call
Deutsche Bank 26 Sep 2025 43.00 (174.76%) Buy 16.24
BTIG 16 Sep 2025 70.00 (347.28%) Buy 14.82

No data within this time range.

The support, resistance and trendline levels presented has been generated by an artificial intelligence (AI) model and should be interpreted with caution.

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