SPYRE THERAPEUTICS INC.

NASDAQ: SYRE (Spyre Therapeutics, Inc.)

Last update: 5 days ago, 1:59PM

90.33

-2.00 (-2.17%)

Previous Close 92.33
Open 91.90
Volume 503,013
Avg. Volume (3M) 1,228,921
Market Cap 8,441,522,176
Price / Book 8.14
52 Weeks Range
21.15 (-76%) — 110.18 (21%)
Earnings Date 3 Nov 2026
Diluted EPS (TTM) -3.06
Total Debt/Equity (MRQ) 0.06%
Current Ratio (MRQ) 8.06
Operating Cash Flow (TTM) -169.86 M
Levered Free Cash Flow (TTM) -68.57 M
Return on Assets (TTM) -25.34%
Return on Equity (TTM) -65.82%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Mixed Bullish
Biotechnology (Global) Mixed Bullish
Stock Spyre Therapeutics, Inc. Mixed Bullish

AIStockmoo Score

0.2
Analyst Consensus NA
Insider Activity NA
Price Volatility -2.0
Technical Moving Averages -1.0
Technical Oscillators 4.0
Relative Valuation NA
Financial Health NA
Macro Environment -0.3
AI Insight NA
Weighted Average 0.19

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SYRE 8 B - - 8.14
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RIGL - - - 2.26

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Spyre Therapeutics Inc is a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (IBD) and rheumatic diseases. Spyre's pipeline includes extended half-life antibodies targeting α4β7, TL1A, and IL-23 in development as monotherapies and pair-wise combinations. It has a single reportable segment, which is the development of biopharmaceutical products for the treatment of patients with IBD and other immune-mediated disease.

Sector Healthcare
Industry Biotechnology
Investment Style Small Growth
% Held by Insiders 8.71%
% Held by Institutions 106.07%

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