SPYRE THERAPEUTICS INC.

NASDAQ: SYRE (Spyre Therapeutics, Inc.)

Last update: 18 Jun, 4:17PM

88.34

0.85 (0.97%)

Previous Close 87.49
Open 89.55
Volume 1,965,671
Avg. Volume (3M) 1,183,260
Market Cap 7,671,556,096
Price / Sales 650.22
Price / Book 14.54
52 Weeks Range
14.00 (-84%) — 90.99 (2%)
Earnings Date 4 Aug 2026
Diluted EPS (TTM) -3.06
Total Debt/Equity (MRQ) 0.06%
Current Ratio (MRQ) 8.06
Operating Cash Flow (TTM) -169.86 M
Levered Free Cash Flow (TTM) -68.57 M
Return on Assets (TTM) -25.34%
Return on Equity (TTM) -65.82%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Mixed Bullish
Biotechnology (Global) Mixed Bullish
Stock Spyre Therapeutics, Inc. Mixed Bullish

AIStockmoo Score

0.4
Analyst Consensus NA
Insider Activity 0.0
Price Volatility -5.0
Technical Moving Averages 2.5
Technical Oscillators 4.0
Average 0.38

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Spyre Therapeutics Inc is a biotechnology company that aims to create the next-generation of inflammatory bowel disease (IBD) products by combining antibody engineering, rational therapeutic combinations, and precision medicine approaches for patient selection. IBD is a chronic condition characterized by inflammation within the gastrointestinal tract, including two main disorders which are UC and CD. It has a single reportable segment, which is the development of biopharmaceutical products for the treatment of patients with IBD and other immune-mediated disease.

Sector Healthcare
Industry Biotechnology
Investment Style Small Value
% Held by Insiders 8.71%
% Held by Institutions 106.07%

No data within this time range.

Name Avg. Buy ($) Avg. Sell ($) Net Quantity Net Value ($)
FAIRMOUNT FUNDS MANAGEMENT LLC 97.05 97.05 -4,018,101 -389,956,702
HENDERSON MICHAEL THOMAS - 100.32 -20,000 -2,006,400
Aggregate Net Quantity -4,038,101
Aggregate Net Value ($) -391,963,102
Aggregate Avg. Buy ($) 97.05
Aggregate Avg. Sell ($) 98.69
Insider Range ($)
97.05 (9%) — 100.32 (13%)
Name Holder Date Type Quantity Price Value ($)
FAIRMOUNT FUNDS MANAGEMENT LLC Director 23 Jun 2026 Acquired (+) 666,680 97.05 64,701,294
FAIRMOUNT FUNDS MANAGEMENT LLC Director 23 Jun 2026 Sell (-) 4,684,781 97.05 454,657,996
HENDERSON MICHAEL THOMAS Director 22 Jun 2026 Automatic sell (-) 20,000 100.32 2,006,400

The support, resistance and trendline levels presented has been generated by an artificial intelligence (AI) model and should be interpreted with caution.

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