SPYRE THERAPEUTICS INC.

NASDAQ: SYRE (Spyre Therapeutics, Inc.)

Last update: 26 May, 7:50PM

73.65

-0.40 (-0.54%)

Previous Close 74.05
Open 74.87
Volume 470,325
Avg. Volume (3M) 1,115,526
Market Cap 6,395,858,432
Price / Sales 650.22
Price / Book 13.23
52 Weeks Range
13.93 (-81%) — 78.80 (6%)
Earnings Date 4 Aug 2026
Diluted EPS (TTM) -3.06
Total Debt/Equity (MRQ) 0.06%
Current Ratio (MRQ) 8.06
Operating Cash Flow (TTM) -169.86 M
Levered Free Cash Flow (TTM) -68.57 M
Return on Assets (TTM) -25.34%
Return on Equity (TTM) -65.82%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Bullish Mixed
Biotechnology (Global) Bullish Mixed
Stock Spyre Therapeutics, Inc. Bearish Bearish

AIStockmoo Score

-2.0
Analyst Consensus -2.0
Insider Activity -4.0
Price Volatility -5.0
Technical Moving Averages 0.0
Technical Oscillators 1.0
Average -2.00

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Spyre Therapeutics Inc is a biotechnology company that aims to create the next-generation of inflammatory bowel disease (IBD) products by combining antibody engineering, rational therapeutic combinations, and precision medicine approaches for patient selection. IBD is a chronic condition characterized by inflammation within the gastrointestinal tract, including two main disorders which are UC and CD. It has a single reportable segment, which is the development of biopharmaceutical products for the treatment of patients with IBD and other immune-mediated disease.

Sector Healthcare
Industry Biotechnology
Investment Style Small Value
% Held by Insiders 8.71%
% Held by Institutions 106.07%

No data within this time range.

Name Avg. Buy ($) Avg. Sell ($) Net Quantity Net Value ($)
BURROWS SCOTT L - 70.54 -7,500 -529,050
SLOAN SHELDON - 73.52 -8,333 -612,642
TURTLE CAMERON - 70.54 -15,000 -1,058,100
Aggregate Net Quantity -30,833
Aggregate Net Value ($) -2,199,792
Aggregate Avg. Buy ($) -
Aggregate Avg. Sell ($) 71.53
Name Holder Date Type Quantity Price Value ($)
SLOAN SHELDON Officer 03 Jun 2026 Automatic sell (-) 8,333 73.52 612,642
SLOAN SHELDON Officer 03 Jun 2026 Option execute 8,333 - -
BURROWS SCOTT L Officer 01 Jun 2026 Automatic sell (-) 7,500 70.54 529,050
BURROWS SCOTT L Officer 01 Jun 2026 Option execute 7,500 - -
TURTLE CAMERON Officer 01 Jun 2026 Automatic sell (-) 15,000 70.54 1,058,100

The support, resistance and trendline levels presented has been generated by an artificial intelligence (AI) model and should be interpreted with caution.

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