TAYSHA GENE THERAPIES INC

NASDAQ: TSHA (Taysha Gene Therapies, Inc.)

Last update: 5 hours ago

4.72

0.06 (1.29%)

Previous Close 4.66
Open 4.65
Volume 1,303,874
Avg. Volume (3M) 3,255,008
Market Cap 1,292,899,328
Price / Sales 212.62
Price / Book 5.64
52 Weeks Range
1.05 (-77%) — 6.02 (27%)
Earnings Date 4 Nov 2025
Operating Margin (TTM) -930.54%
Diluted EPS (TTM) -0.340
Quarterly Revenue Growth (YOY) -32.50%
Total Debt/Equity (MRQ) 111.93%
Current Ratio (MRQ) 5.35
Operating Cash Flow (TTM) -83.45 M
Levered Free Cash Flow (TTM) -52.28 M
Return on Assets (TTM) -35.91%
Return on Equity (TTM) -159.34%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Bullish Mixed
Biotechnology (Global) Bullish Mixed
Stock Taysha Gene Therapies, Inc. Bearish Bullish

AIStockmoo Score

-0.9
Analyst Consensus 2.0
Insider Activity -4.0
Price Volatility -4.5
Technical Moving Averages 2.5
Technical Oscillators -0.5
Average -0.90

Similar Stocks

Stock Market Cap DY P/E (TTM) P/B
TSHA 1 B - - 5.64
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MESO 2 B - - 3.73
DFTX 2 B - - 12.73
SANA 1 B - - 6.26

Taysha Gene Therapies Inc is a patient-centric gene therapy company to eradicate monogenic CNS disease. It is focused on developing and commercializing AAV-based gene therapies for the treatment of monogenic diseases of the CNS in both rare and large patient populations. The company develops and commercializes transformative gene therapy treatments. Its product pipeline includes, TSHA-102 which is a is a self-complementary intrathecally delivered AAV9 gene transfer therapy in clinical evaluation for Rett syndrome.

Sector Healthcare
Industry Biotechnology
Investment Style Small Value
% Held by Insiders 12.11%
% Held by Institutions 67.23%

Ownership

Name Date Shares Held
Avoro Capital Advisors Llc 30 Sep 2025 21,700,000
Siren, L.L.C. 30 Sep 2025 11,014,737
Octagon Capital Advisors Lp 30 Sep 2025 9,067,500
Vestal Point Capital, Lp 30 Sep 2025 5,500,000
Deerfield Management Company, L.P. 30 Sep 2025 5,386,000
Polar Capital Holdings Plc 30 Sep 2025 5,293,879
52 Weeks Range
1.05 (-77%) — 6.02 (27%)
Price Target Range
8.00 (69%) — 12.00 (154%)
High 12.00 (Chardan Capital, 154.24%) Buy
Median 11.00 (133.05%)
Low 8.00 (Citizens, 69.49%) Buy
Average 10.33 (118.86%)
Total 3 Buy
Avg. Price @ Call 4.73
Firm Date Target Price Call Price @ Call
Chardan Capital 06 Jan 2026 12.00 (154.24%) Buy 5.26
05 Nov 2025 12.00 (154.24%) Buy 4.03
Wells Fargo 05 Jan 2026 11.00 (133.05%) Buy 4.89
Citizens 05 Nov 2025 8.00 (69.49%) Buy 4.03
Name Avg. Buy ($) Avg. Sell ($) Net Quantity Net Value ($)
ALAM KAMRAN - 4.69 -102,817 -480,558
NAGENDRAN SUKUMAR - 4.69 -116,050 -542,408
NOLAN SEAN P. - 4.69 -178,101 -832,429
Aggregate Net Quantity -396,968
Aggregate Net Value ($) -1,855,396
Aggregate Avg. Buy ($) -
Aggregate Avg. Sell ($) 4.69
Name Holder Date Type Quantity Price Value ($)
ALAM KAMRAN Officer 26 Jan 2026 Sell (-) 23,849 4.72 112,567
NOLAN SEAN P. Officer 26 Jan 2026 Sell (-) 41,312 4.72 194,993
NAGENDRAN SUKUMAR Officer 26 Jan 2026 Sell (-) 26,918 4.72 127,053
ALAM KAMRAN Officer 23 Jan 2026 Sell (-) 78,968 4.66 367,991
NOLAN SEAN P. Officer 23 Jan 2026 Sell (-) 136,789 4.66 637,437
NAGENDRAN SUKUMAR Officer 23 Jan 2026 Sell (-) 89,132 4.66 415,355

The support, resistance and trendline levels presented has been generated by an artificial intelligence (AI) model and should be interpreted with caution.

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