KARYOPHARM THERAPEUTICS INC

NASDAQ: KPTI (Karyopharm Therapeutics Inc.)

Last update: 08 Mar, 2:48AM

6.89

0.67 (10.77%)

Previous Close 6.22
Open 6.24
Volume 159,634
Avg. Volume (3M) 88,425
Market Cap 57,986,240
Price / Sales 0.370
52 Weeks Range
5.90 (-14%) — 24.75 (259%)
Earnings Date 6 May 2025 - 12 May 2025
Profit Margin -52.62%
Operating Margin (TTM) -102.42%
Diluted EPS (TTM) -13.95
Quarterly Revenue Growth (YOY) -9.50%
Current Ratio (MRQ) 1.70
Operating Cash Flow (TTM) -127.49 M
Levered Free Cash Flow (TTM) -77.12 M
Return on Assets (TTM) -36.88%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Mixed Mixed
Biotechnology (Global) Mixed Mixed
Stock Karyopharm Therapeutics Inc. Bullish Bullish

AIStockmoo Score

0.3
Analyst Consensus 3.5
Insider Activity 1.5
Price Volatility 0.5
Technical Moving Averages -1.5
Technical Oscillators -2.5
Average 0.30

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Karyopharm Therapeutics Inc is a commercial-stage pharmaceutical company pioneering novel cancer therapies and dedicated to the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. XPOVIO (selinexor), is approved in the U.S. in multiple hematologic malignancy indications, including in combination with Velcade (bortezomib) and dexamethasone for the treatment of adult patients with multiple myeloma after at least one prior therapy, in combination with dexamethasone for the treatment of adult patients with heavily pretreated multiple myeloma and as a monotherapy for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma. The company derives its revenue from United States.

Sector Healthcare
Industry Biotechnology
Investment Style Small Value
% Held by Insiders 6.86%
% Held by Institutions 49.36%
52 Weeks Range
5.90 (-14%) — 24.75 (259%)
Price Target Range
3.00 (-56%) — 56.00 (712%)
High 56.00 (HC Wainwright & Co., 712.77%) Buy
Median 54.00 (683.75%)
Low 3.00 (RBC Capital, -56.46%) Buy
Average 37.67 (446.73%)
Total 3 Buy
Avg. Price @ Call 8.74
Firm Date Target Price Call Price @ Call
Baird 03 Mar 2025 54.00 (683.74%) Buy 7.25
HC Wainwright & Co. 26 Feb 2025 56.00 (712.77%) Buy 9.83
20 Feb 2025 7.00 (1.60%) Buy 9.15
RBC Capital 20 Feb 2025 3.00 (-56.46%) Buy 9.15
10 Feb 2025 3.00 (-56.46%) Buy 9.35
Name Avg. Buy ($) Avg. Sell ($) Net Quantity Net Value ($)
ABATE KRISTIN - 6.37 -571 -3,637
CHENG SOHANYA ROSHAN - 6.37 -3,445 -21,945
MANO MICHAEL - 6.37 -2,793 -17,791
PAULSON RICHARD A. - 6.37 -11,694 -74,491
POULTON STUART - 6.37 -3,548 -22,601
RANGWALA RESHMA - 6.37 -3,587 -22,849
Aggregate Net Quantity -25,638
Aggregate Net Value ($) -163,314
Aggregate Avg. Buy ($) -
Aggregate Avg. Sell ($) 6.37
Name Holder Date Type Quantity Price Value ($)
MANO MICHAEL Officer 04 Mar 2025 Sell (-) 2,793 6.37 17,791
ABATE KRISTIN Officer 04 Mar 2025 Sell (-) 571 6.37 3,637
POULTON STUART Officer 04 Mar 2025 Sell (-) 3,548 6.37 22,601
PAULSON RICHARD A. Officer 04 Mar 2025 Sell (-) 11,694 6.37 74,491
CHENG SOHANYA ROSHAN Officer 04 Mar 2025 Sell (-) 3,445 6.37 21,945
RANGWALA RESHMA Officer 04 Mar 2025 Sell (-) 3,587 6.37 22,849

The support, resistance and trendline levels presented has been generated by an artificial intelligence (AI) model and should be interpreted with caution.

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