KARYOPHARM THERAPEUTICS INC

NASDAQ: KPTI (Karyopharm Therapeutics Inc.)

Last update: 17 hours ago

1.92

-5.09 (-72.61%)

Previous Close 7.01
Open 2.19
Volume 22,094,624
Avg. Volume (3M) 923,288
Market Cap 43,512,852
Price / Sales 0.730
52 Weeks Range
1.80 (-6%) — 10.99 (472%)
Earnings Date 11 Aug 2026
Profit Margin -43.99%
Operating Margin (TTM) -110.80%
Diluted EPS (TTM) -11.87
Quarterly Revenue Growth (YOY) -9.40%
Current Ratio (MRQ) 1.33
Operating Cash Flow (TTM) -122.75 M
Levered Free Cash Flow (TTM) -72.22 M
Return on Assets (TTM) -44.76%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Mixed Bullish
Biotechnology (Global) Mixed Bullish
Stock Karyopharm Therapeutics Inc. Mixed Bearish

AIStockmoo Score

0.8
Analyst Consensus NA
Insider Activity NA
Price Volatility 3.0
Technical Moving Averages 0.0
Technical Oscillators -0.5
Average 0.83

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VOR 1 B - - 0.660
CVAC 1 B - 5.08 1.03

Karyopharm Therapeutics Inc is a commercial-stage pharmaceutical company pioneering novel cancer therapies and dedicated to the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. XPOVIO (selinexor), is approved in the U.S. in multiple hematologic malignancy indications, including in combination with Velcade (bortezomib) and dexamethasone for the treatment of adult patients with multiple myeloma after at least one prior therapy, in combination with dexamethasone for the treatment of adult patients with heavily pretreated multiple myeloma and as a monotherapy for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma. The company derives its revenue from United States.

Sector Healthcare
Industry Biotechnology
Investment Style Small Value
% Held by Insiders 6.33%
% Held by Institutions 42.78%

Ownership

Name Date Shares Held
Catalio Capital Management, Lp 31 Mar 2026 897,709
Avidity Partners Management Lp 31 Mar 2026 463,741
Soleus Capital Management, L.P. 31 Mar 2026 440,000
Boxer Capital Management, Llc 31 Mar 2026 302,536

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The support, resistance and trendline levels presented has been generated by an artificial intelligence (AI) model and should be interpreted with caution.

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