MADRIGAL PHARMACEUTICALS INC

NASDAQ: MDGL (Madrigal Pharmaceuticals, Inc.)

Last update: yesterday, 9:53AM

591.02

46.61 (8.56%)

Previous Close 544.41
Open 552.42
Volume 889,146
Avg. Volume (3M) 342,995
Market Cap 13,422,904,320
Price / Sales 17.11
Price / Book 20.74
52 Weeks Range
265.00 (-55%) — 605.00 (2%)
Earnings Date 4 Nov 2025
Profit Margin -123.38%
Operating Margin (TTM) -57.79%
Diluted EPS (TTM) -17.83
Total Debt/Equity (MRQ) 16.85%
Current Ratio (MRQ) 5.91
Operating Cash Flow (TTM) -395.31 M
Levered Free Cash Flow (TTM) -274.11 M
Return on Assets (TTM) -25.56%
Return on Equity (TTM) -50.16%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Bullish Mixed
Biotechnology (Global) Bullish Mixed
Stock Madrigal Pharmaceuticals, Inc. Bullish Bullish

AIStockmoo Score

-1.0
Analyst Consensus 1.5
Insider Activity -3.0
Price Volatility -3.0
Technical Moving Averages -1.0
Technical Oscillators 0.5
Average -1.00

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Madrigal Pharmaceuticals Inc is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease with high unmet medical need that can lead to cirrhosis, liver failure, and premature mortality. The company's medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed thyroid hormone receptor agonist designed to target key underlying causes of MASH.

Sector Healthcare
Industry Biotechnology
Investment Style Small Growth
% Held by Insiders 7.73%
% Held by Institutions 108.28%
52 Weeks Range
265.00 (-55%) — 605.00 (2%)
Price Target Range
445.00 (-24%) — 900.00 (52%)
High 900.00 (Piper Sandler, 52.28%) Buy
Median 630.00 (6.60%)
Low 445.00 (B of A Securities, -24.71%) Hold
Average 629.88 (6.58%)
Total 7 Buy, 1 Hold
Avg. Price @ Call 526.40
Firm Date Target Price Call Price @ Call
Piper Sandler 19 Dec 2025 900.00 (52.28%) Buy 591.02
15 Oct 2025 540.00 (-8.63%) Buy 433.45
B. Riley Securities 11 Dec 2025 670.00 (13.36%) Buy 571.33
29 Sep 2025 560.00 (-5.25%) Buy 443.10
HC Wainwright & Co. 21 Nov 2025 620.00 (4.90%) Buy 547.96
11 Nov 2025 568.00 (-3.89%) Buy 541.50
Oppenheimer 20 Nov 2025 650.00 (9.98%) Buy 542.12
10 Oct 2025 590.00 (-0.17%) Buy 429.60
Truist Securities 19 Nov 2025 640.00 (8.29%) Buy 555.60
15 Oct 2025 580.00 (-1.86%) Buy 433.45
Canaccord Genuity 13 Nov 2025 587.00 (-0.68%) Buy 514.93
Citizens 05 Nov 2025 527.00 (-10.83%) Buy 475.87
B of A Securities 03 Nov 2025 445.00 (-24.71%) Hold 412.35
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Name Avg. Buy ($) Avg. Sell ($) Net Quantity Net Value ($)
FRIEDMAN PAUL A - 552.47 -24,800 -13,701,256
TAUB REBECCA - 552.47 -24,105 -13,317,289
Aggregate Net Quantity -48,905
Aggregate Net Value ($) -27,018,545
Aggregate Avg. Buy ($) -
Aggregate Avg. Sell ($) 552.47
Name Holder Date Type Quantity Price Value ($)
TAUB REBECCA Director 10 Dec 2025 Automatic sell (-) 18,650 552.47 10,303,566
TAUB REBECCA Director 10 Dec 2025 Disposed (-) 5,455 552.47 3,013,724
TAUB REBECCA Director 10 Dec 2025 Option execute 18,650 - -
FRIEDMAN PAUL A Director 10 Dec 2025 Automatic sell (-) 24,800 552.47 13,701,256
FRIEDMAN PAUL A Director 10 Dec 2025 Option execute 24,800 - -
Date Type Details
18 Dec 2025 Announcement Madrigal Pharmaceuticals Announces Grants of Inducement Awards under Nasdaq Listing Rule 5635(c)(4)
15 Dec 2025 Announcement Madrigal Pharmaceuticals to Present at the 44th Annual J.P. Morgan Healthcare Conference
04 Dec 2025 Announcement Madrigal Pharmaceuticals Announces Grants of Inducement Awards under Nasdaq Listing Rule 5635(c)(4)
20 Nov 2025 Announcement Madrigal Pharmaceuticals Announces Grants of Inducement Awards under Nasdaq Listing Rule 5635(c)(4)
17 Nov 2025 Announcement Madrigal Pharmaceuticals Announces Participation at Three Upcoming Investor Conferences
10 Nov 2025 Announcement Madrigal Presents New Data Demonstrating Rezdiffra® (resmetirom) Significantly Improved Multiple Noninvasive Imaging Tests and Biomarkers in Patients with Compensated MASH Cirrhosis
06 Nov 2025 Announcement Madrigal Pharmaceuticals Announces Grants of Inducement Awards under Nasdaq Listing Rule 5635(c)(4)
04 Nov 2025 Announcement Madrigal Pharmaceuticals Reports Third-Quarter 2025 Financial Results and Provides Corporate Updates
28 Oct 2025 Announcement Madrigal to Present New Data from the Company’s MASH Program at AASLD’s The Liver Meeting 2025
22 Oct 2025 Announcement Madrigal Pharmaceuticals to Release Third-Quarter 2025 Financial Results and Host Webcast on November 4, 2025
21 Oct 2025 Announcement Madrigal Pharmaceuticals Announces Grants of Inducement Awards under Nasdaq Listing Rule 5635(c)(4)
07 Oct 2025 Announcement Madrigal Pharmaceuticals Announces Grants of Inducement Awards under Nasdaq Listing Rule 5635(c)(4)
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