NUVALENT INC

NASDAQ: NUVL (Nuvalent, Inc.)

Last update: 10 hours ago

106.86

-0.04 (-0.04%)

Previous Close 106.90
Open 106.38
Volume 413,492
Avg. Volume (3M) 575,346
Market Cap 7,769,439,232
Price / Book 10.04
52 Weeks Range
55.54 (-48%) — 112.88 (5%)
Earnings Date 30 Oct 2025
Diluted EPS (TTM) -4.42
Current Ratio (MRQ) 14.48
Operating Cash Flow (TTM) -203.80 M
Levered Free Cash Flow (TTM) -98.58 M
Return on Assets (TTM) -22.23%
Return on Equity (TTM) -35.69%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Mixed Mixed
Biotechnology (Global) Mixed Mixed
Stock Nuvalent, Inc. Bullish Bullish

AIStockmoo Score

1.2
Analyst Consensus 4.0
Insider Activity -1.5
Price Volatility -3.0
Technical Moving Averages 2.5
Technical Oscillators 4.0
Average 1.20

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Nuvalent Inc is a clinical-stage biopharmaceutical company focused on creating precisely targeted therapies for patients with cancer. All of the Company’s operations are in the United States. The company is engaged in developing small molecules that are designed to overcome the limitations of existing therapies for clinically validated kinase targets. The product candidates of the company include NVL-520, which is being developed for patients with ROS1-positive non-small cell lung cancer (NSCLC), NVL-655, which is being developed for patients with anaplastic lymphoma kinase (ALK)-positive NSCLC, NVL-330, is a brain-penetrant human epidermal growth factor receptor 2 (HER2)-selective inhibitor designed to address the combined medical need of treating tumors driven by HER2ex20.

Sector Healthcare
Industry Biotechnology
Investment Style Small Core
% Held by Insiders 2.85%
% Held by Institutions 110.02%

Ownership

Name Date Shares Held
Perceptive Advisors Llc 30 Sep 2025 1,562,336
52 Weeks Range
55.54 (-48%) — 112.88 (5%)
Price Target Range
112.00 (4%) — 158.00 (47%)
High 158.00 (Baird, 47.86%) Buy
Median 135.00 (26.33%)
Low 112.00 (Barclays, 4.81%) Buy
Average 136.54 (27.78%)
Total 13 Buy
Avg. Price @ Call 100.70
Firm Date Target Price Call Price @ Call
Truist Securities 24 Nov 2025 140.00 (31.01%) Buy 109.53
Baird 18 Nov 2025 158.00 (47.86%) Buy 104.24
Goldman Sachs 18 Nov 2025 135.00 (26.33%) Buy 104.24
Guggenheim 18 Nov 2025 155.00 (45.05%) Buy 104.24
HC Wainwright & Co. 17 Nov 2025 155.00 (45.05%) Buy 108.00
Leerink Partners 17 Nov 2025 149.00 (39.43%) Buy 108.00
Stifel 17 Nov 2025 135.00 (26.33%) Buy 108.00
16 Oct 2025 115.00 (7.62%) Buy 90.42
Canaccord Genuity 12 Nov 2025 126.00 (17.91%) Buy 97.03
Barclays 31 Oct 2025 112.00 (4.81%) Buy 99.32
UBS 31 Oct 2025 132.00 (23.53%) Buy 99.32
Piper Sandler 27 Oct 2025 128.00 (19.78%) Buy 97.71
Cantor Fitzgerald 15 Oct 2025 135.00 (26.33%) Buy 89.64
Wedbush 08 Sep 2025 115.00 (7.62%) Buy 79.83
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Name Avg. Buy ($) Avg. Sell ($) Net Quantity Net Value ($)
FLYNN JAMES E - 109.53 -742,574 -81,334,130
SHAIR MATTHEW - 109.53 -7,500 -821,475
Aggregate Net Quantity -750,074
Aggregate Net Value ($) -82,155,605
Aggregate Avg. Buy ($) -
Aggregate Avg. Sell ($) 109.53
Name Holder Date Type Quantity Price Value ($)
FLYNN JAMES E Director 24 Nov 2025 Sell (-) 742,574 109.53 81,334,130
SHAIR MATTHEW Director 24 Nov 2025 Automatic sell (-) 5,850 109.53 640,751
SHAIR MATTHEW Director 24 Nov 2025 Automatic sell (-) 1,650 109.53 180,725
Date Type Details
26 Nov 2025 Announcement Nuvalent to Participate in the Piper Sandler 37th Annual Healthcare Conference
24 Nov 2025 Announcement Nuvalent Announces Closing of Public Offering of Common Stock and Full Exercise by Underwriters of Option to Purchase Additional Shares from Selling Stockholders
19 Nov 2025 Announcement Nuvalent Announces FDA Acceptance of New Drug Application for Zidesamtinib for the Treatment of TKI Pre-treated Patients with Advanced ROS1-positive NSCLC
17 Nov 2025 Announcement Nuvalent Announces Public Offering of Common Stock
17 Nov 2025 Announcement Nuvalent Announces Positive Topline Pivotal Data from ALKOVE-1 Clinical Trial of Neladalkib for TKI Pre-treated Patients with Advanced ALK-positive NSCLC
14 Nov 2025 Announcement Nuvalent Announces Timing of Topline Pivotal Data for TKI Pre-treated Patients with Advanced ALK-positive NSCLC from ALKOVE-1 Clinical Trial of Neladalkib
04 Nov 2025 Announcement Nuvalent to Present Patient-Reported Outcomes Data from ARROS-1 Trial of ROS1-Selective Inhibitor, Zidesamtinib, at 2025 IASLC ASCO North America Conference on Lung Cancer
30 Oct 2025 Announcement Nuvalent Highlights Recent Pipeline Progress, Reiterates Key Anticipated Milestones, and Reports Third Quarter 2025 Financial Results
18 Oct 2025 Announcement Nuvalent Presents Preliminary Data for Neladalkib in Advanced ALK-positive Solid Tumors Beyond NSCLC at ESMO 2025
13 Oct 2025 Announcement Nuvalent to Present New Preclinical Data for HER2-Selective Inhibitor, NVL-330, at AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
24 Sep 2025 Announcement Nuvalent to Participate in the UBS 2025 Virtual Oncology Day
07 Sep 2025 Announcement Nuvalent Presents Pivotal Data from ARROS-1 Clinical Trial of Zidesamtinib for TKI Pre-treated Patients with Advanced ROS1-positive NSCLC at WCLC 2025
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