PRAXIS PRECISION MEDICINES INC

NASDAQ: PRAX (Praxis Precision Medicines, Inc)

Last update: 10 hours ago

312.60

-11.48 (-3.54%)

Previous Close 324.08
Open 322.82
Volume 489,122
Avg. Volume (3M) 810,409
Market Cap 8,671,177,728
Price / Sales 842.93
Price / Book 24.04
52 Weeks Range
26.70 (-91%) — 326.91 (4%)
Earnings Date 5 Nov 2025
Operating Margin (TTM) -2,868.84%
Diluted EPS (TTM) -10.66
Quarterly Revenue Growth (YOY) 1,349.10%
Total Debt/Equity (MRQ) 0.24%
Current Ratio (MRQ) 8.44
Operating Cash Flow (TTM) -163.91 M
Levered Free Cash Flow (TTM) -90.04 M
Return on Assets (TTM) -39.95%
Return on Equity (TTM) -63.56%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Mixed Mixed
Biotechnology (Global) Mixed Mixed
Stock Praxis Precision Medicines, Inc Bearish Bullish

AIStockmoo Score

-0.9
Analyst Consensus -0.5
Insider Activity -1.0
Price Volatility -5.0
Technical Moving Averages 0.0
Technical Oscillators 2.0
Average -0.90

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Praxis Precision Medicines Inc is a clinical-stage biopharmaceutical company. The firm is engaged in translating genetic insights into the development of therapies for patients affected by central nervous system disorders characterized by a neuronal excitation-inhibition imbalance. The company has generated three clinical-stage product candidates, ulixacaltamide (formerly known as PRAX-944), vormatrigine (formerly known as PRAX-628), and relutrigine (formerly known as PRAX-562), as well as PRAX-020 which has been in-licensed by UCB Biopharma SRL, or UCB.

Sector Healthcare
Industry Biotechnology
Investment Style Small Growth
% Held by Insiders 0.16%
% Held by Institutions 122.02%

Ownership

Name Date Shares Held
Perceptive Advisors Llc 30 Sep 2025 1,564,554
Cormorant Asset Management, Lp 30 Sep 2025 1,000,000
Deerfield Management Company, L.P. 30 Sep 2025 840,851
Baker Bros. Advisors Lp 30 Sep 2025 689,488
52 Weeks Range
26.70 (-91%) — 326.91 (4%)
Price Target Range
95.00 (-69%) — 843.00 (169%)
High 843.00 (BTIG, 169.67%) Buy
Median 450.00 (43.95%)
Low 95.00 (Wedbush, -69.61%) Sell
Average 489.56 (56.61%)
Total 8 Buy, 1 Sell
Avg. Price @ Call 272.99
Firm Date Target Price Call Price @ Call
Wedbush 12 Jan 2026 95.00 (-69.61%) Sell 275.74
05 Dec 2025 83.00 (-73.45%) Sell 247.99
BTIG 29 Dec 2025 843.00 (169.67%) Buy 304.58
08 Dec 2025 507.00 (62.19%) Buy 270.98
Oppenheimer 15 Dec 2025 750.00 (139.92%) Buy 276.40
Guggenheim 09 Dec 2025 760.00 (143.12%) Buy 258.13
Jefferies 09 Dec 2025 450.00 (43.95%) Buy 258.13
HC Wainwright & Co. 08 Dec 2025 340.00 (8.77%) Buy 270.98
05 Dec 2025 340.00 (8.77%) Buy 247.99
Needham 08 Dec 2025 315.00 (0.77%) Buy 270.98
05 Dec 2025 304.00 (-2.75%) Buy 247.99
TD Cowen 08 Dec 2025 353.00 (12.92%) Buy 270.98
Truist Securities 08 Dec 2025 500.00 (59.95%) Buy 270.98
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Name Avg. Buy ($) Avg. Sell ($) Net Quantity Net Value ($)
KELLY TIMOTHY EDWIN 294.38 282.10 6,522 1,945,440
MASTROCOLA LAUREN 294.38 282.10 3,039 903,209
NEMIROFF ALEX 294.38 282.10 5,190 1,547,586
SNIECINSKI MEGAN 294.38 282.10 7,653 2,275,832
SOUZA MARCIO 294.38 288.45 23,388 6,910,174
Aggregate Net Quantity 45,792
Aggregate Net Value ($) 13,582,242
Aggregate Avg. Buy ($) 294.38
Aggregate Avg. Sell ($) 282.80
Name Holder Date Type Quantity Price Value ($)
KELLY TIMOTHY EDWIN Officer 12 Jan 2026 Disposed (-) 943 275.74 260,023
NEMIROFF ALEX Officer 12 Jan 2026 Disposed (-) 768 275.74 211,768
SNIECINSKI MEGAN Officer 12 Jan 2026 Disposed (-) 885 275.74 244,030
MASTROCOLA LAUREN Officer 12 Jan 2026 Disposed (-) 344 275.74 94,855
SOUZA MARCIO Officer 10 Jan 2026 Disposed (-) 4,252 288.45 1,226,489
KELLY TIMOTHY EDWIN Officer 10 Jan 2026 Disposed (-) 1,335 288.45 385,081
NEMIROFF ALEX Officer 10 Jan 2026 Disposed (-) 917 288.45 264,509
SNIECINSKI MEGAN Officer 10 Jan 2026 Disposed (-) 1,087 288.45 313,545
MASTROCOLA LAUREN Officer 10 Jan 2026 Disposed (-) 367 288.45 105,861
SOUZA MARCIO Officer 08 Jan 2026 Acquired (+) 27,640 294.38 8,136,663
KELLY TIMOTHY EDWIN Officer 08 Jan 2026 Acquired (+) 8,800 294.38 2,590,544
NEMIROFF ALEX Officer 08 Jan 2026 Acquired (+) 6,875 294.38 2,023,863
SNIECINSKI MEGAN Officer 08 Jan 2026 Acquired (+) 9,625 294.38 2,833,408
MASTROCOLA LAUREN Officer 08 Jan 2026 Acquired (+) 3,750 294.38 1,103,925
Show more
Date Type Details
13 Jan 2026 Announcement Praxis Precision Medicines Appoints Global Epilepsy Leader Dr. Orrin Devinsky as Head of Clinical Strategy
12 Jan 2026 Announcement Praxis Precision Medicines Enters Its Next Chapter Following a Pivotal Year of Progress
09 Jan 2026 Announcement Praxis Precision Medicines, Inc. Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
08 Jan 2026 Announcement Praxis Precision Medicines Further Positioned for Next-Phase Growth with Key Board and Executive Appointments
06 Jan 2026 Announcement Praxis Precision Medicines, Inc. Announces Pricing of $575 Million Public Offering
06 Jan 2026 Announcement Praxis Precision Medicines, Inc. Announces Proposed Public Offering
29 Dec 2025 Announcement Praxis Precision Medicines Announces the FDA Has Granted Breakthrough Therapy Designation for Ulixacaltamide HCl in Essential Tremor
11 Dec 2025 Announcement Praxis Precision Medicines Announces Plans to File an NDA for Relutrigine in SCN2A and SCN8A Developmental and Epileptic Encephalopathies in Early 2026
09 Dec 2025 Announcement Praxis Precision Medicines Announces Alignment with FDA on Simplified and Accelerated Registrational Pathway for Elsunersen in Early Onset SCN2A Developmental and Epileptic Encephalopathy
08 Dec 2025 Announcement Praxis AES Wrap-up: Best-in-Class Potential Across Rare Pediatric and Adult Epilepsies
04 Dec 2025 Announcement Praxis Precision Medicines Announces Positive Results from EMBOLD Study for Relutrigine in SCN2A and SCN8A Developmental and Epileptic Encephalopathies
04 Dec 2025 Announcement Praxis Precision Medicines Announces Positive Pre-NDA Meeting with FDA for Ulixacaltamide in Essential Tremor
03 Dec 2025 Announcement Praxis Precision Medicines, Inc. Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
24 Nov 2025 Announcement Praxis to present latest preclinical and clinical advancements across leading epilepsy portfolio at the 2025 American Epilepsy Society (AES) Annual Meeting
20 Nov 2025 Announcement Praxis Precision Medicines to Participate in Upcoming Fireside Chat
06 Nov 2025 Announcement Praxis Precision Medicines, Inc. Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
05 Nov 2025 Announcement Praxis Precision Medicines Provides Corporate Update and Reports Third Quarter 2025 Financial Results
05 Nov 2025 Announcement Praxis Precision Medicines to Participate in Upcoming Investor Conferences
04 Nov 2025 Announcement Praxis announces accelerated development path for relutrigine in SCN2A and SCN8A DEE patients following positive FDA feedback
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