UPSTREAM BIO, INC.

NASDAQ: UPB (Upstream Bio, Inc.)

Last update: 16 hours ago

24.19

-0.65 (-2.62%)

Previous Close 24.84
Open 24.82
Volume 194,891
Avg. Volume (3M) 480,490
Market Cap 1,304,069,120
Price / Sales 367.28
Price / Book 2.45
52 Weeks Range
5.14 (-78%) — 29.46 (21%)
Earnings Date 6 Nov 2025
Operating Margin (TTM) -5,656.01%
Diluted EPS (TTM) -1.67
Quarterly Revenue Growth (YOY) -11.60%
Total Debt/Equity (MRQ) 0.38%
Current Ratio (MRQ) 47.43
Operating Cash Flow (TTM) -82.78 M
Levered Free Cash Flow (TTM) -70.18 M
Return on Assets (TTM) -16.91%
Return on Equity (TTM) -28.62%

Market Trend

Short Term Medium Term
Industry Biotechnology (US) Mixed Mixed
Biotechnology (Global) Mixed Mixed
Stock Upstream Bio, Inc. Bearish Bearish

AIStockmoo Score

0.5
Analyst Consensus -0.5
Insider Activity NA
Price Volatility -1.5
Technical Moving Averages 0.0
Technical Oscillators 4.0
Average 0.50

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ACIU 386 M - - 3.36
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Upstream Bio Inc is a clinical-stage biotechnology company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. It is developing verekitug, the known antagonist currently in clinical development that targets the receptor for Thymic Stromal Lymphopoietin (TSLP), a cytokine that is a clinically validated driver of inflammatory response positioned upstream of multiple signaling cascades that affect a variety of immune-mediated diseases.

Sector Healthcare
Industry Biotechnology
Investment Style Small Growth
% Held by Insiders 14.84%
% Held by Institutions 89.32%
52 Weeks Range
5.14 (-78%) — 29.46 (21%)
Median 47.00 (94.30%)
Total 1 Buy
Firm Date Target Price Call Price @ Call
Truist Securities 14 Oct 2025 47.00 (94.30%) Buy 19.98

No data within this time range.

The support, resistance and trendline levels presented has been generated by an artificial intelligence (AI) model and should be interpreted with caution.

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